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A new study identified Parkinson’s disease-associated compounds from earwax, but some scientists remain skeptical.

Current CRISPR guide RNAs are designed based on European reference genomes, leading to false-negative results in cells from people with African ancestry.

In a model of chronic NAD+ depletion that mimics aging, mitochondria are revealed as a rheostat of cellular NAD+ levels.

New research suggests that long-distance running triggers a temporary change in brain structure.

The Scientist is excited to announce the winners of our 2025 science writing contest!

New research helps unlock the secret to staying safe from wildfire smoke.

A genetically diverse mouse model allowed researchers to identify genes that promote the success of immune checkpoint inhibitors against cancer.

Scientists identified the mechanism by which a sea cucumber molecule inhibits sulfatase-2, an enzyme that’s often upregulated in cancer.

Microbiomes in older mice pumped out damaging metabolites that drove endothelial cell senescence, offering potential targets for therapeutic intervention.

Distinct microRNA signatures in the saliva of people with endometriosis provide a basis for a non-invasive diagnostic test and shed light on disease biology.

Absence of cysteine in mice coaxed fat-storing cells to burn energy, causing weight loss and offering potential therapeutic targets to improve metabolic health.

A receptor on macrophages dictated their ability to reduce inflammation after liver transplant, offering potential therapeutic targets to avoid complications.