CDC, JUDY SCHMIDTIf the risks are low, researchers could be permitted to study the anthrax vaccine in children, according to a 146-page report released today (March 19) by the Presidential Commission for the Study of Bioethical Issues. The commission was tasked with investigating the issue in the fall of 2011 after the National Biodefense Science Board (NBSB) recommended trial of the anthrax vaccine in children.
“This was one of the most difficult ethical reviews that any bioethics commission has ever conducted,” the commission's chair, Amy Gutmann, president of the University of Pennsylvania, told ScienceInsider. On one hand, understanding appropriate usage and dosage of such a vaccine in children is critical for an effective response in the face of a bioterrorist threat. On the other hand, the study would likely expose children to certain risks and may offer no benefit to trial participants.
In weighing these considerations, the commission emphasized that the risks, such as soreness around an injection site, should be “minimal.” Such risks could be demonstrated in a study of young adults, such as those in the US military who have already received the vaccine—made from an inactivated protein ...
