Genetics

GENETIC PREDISPOSITION TO VITAMIN D DEFICIENCY CONTRIBUTES TO SEVERE COVID-19

Genetic Predisposition to Vitamin D Deficiency Contributes to Severe COVID-19

To flag neurons that have experienced genotoxic stress, researchers developed an in vivo sensor using an adeno-associated viral vector, called PRISM. Because a cell’s DNA damage response (DDR)—which activates in response to stressors such as environmental toxins or the buildup of misfolded proteins—also responds to invading pathogens, PRISM has an easier time transfecting cells whose damage response mechanisms are preoccupied with existing DNA damage. Once inside, the virus hijacks the neuron’s DNA replication machinery, which reverts an engineered frameshift mutation in the virus and thereby prompts the production of a fluorescent protein that can be observed via microscopy.

Infographic: DNA Damage Viewed with Unprecedented Clarity

Broken DNA

DNA Damage Viewed with Unprecedented Clarity

Artist’s rendition of a blue-green DNA double helix, viewed lengthwise from within one end.

Stem Cell Lines Riddled With Undetected Mutations

Building with sign reading “Novartis”

Two Children Die After Receiving Novartis Gene Therapy

Explore the importance of cellular diversity in health and disease through single cell resolution.

Single Cell Resolution Reveals Cellular Diversity

A magnifying glass examining a double-helix DNA strand.

Targeted Next-Generation Sequencing with myBaits

Learn about a benchtop centrifugation system improving cell viability and recovery

Automating Gene and Cell Therapy Manufacturing

A male and female lizard sit together on a fence post with grass in the foreground

Climate Change Prematurely Ages Lizards Before They’re Born

Learn How Engineered Cell Libraries Streamline Target Identification Workflows

Engineered Cell Libraries for Targeted Therapeutics Development

A twisted and folded illustration of single-stranded RNA in front of a blue background.

Deficient RNA Editing Implicated in Inflammatory Disease 

genome sequence text on screen 

Q&A: Whole Genomes of 150,000 Britons Reveal Novel Genetic Variants

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Illustration of a hole in the shape of a dollar sign on a blue background. One character is falling into the hole at the bottom of the “S” while another individual is holding another up at the top of the “S”. The image represents the absence of funding for researchers in biotech with the cancellation of the SBIR/STTR program.

The Federal Government’s Research Innovation Lifeline Has Gone Dark

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

An illustration of an in vitro fertilized embryo, which researchers recently used to study maternal aneuploidy

Genetic Basis of Aneuploidy, Which Often Causes Pregnancy Loss, Revealed

A mouse aorta with immunofluorescence tagging of various molecules, emphasizing the close connection between vasculature and fat.

How Fat Type Shapes Hypertension Risk

Multimedia

Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.
January 2026

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

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Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

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Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

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Sino Biological's Launch of SwiftFluo® TR-FRET Kits Pioneers a New Era in High-Throughout Kinase Inhibitor Screening

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SPT Labtech enables automated Twist Bioscience NGS library preparation workflows on SPT's firefly platform

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Nuclera eProtein Discovery System installed at leading Universities in Taiwan

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BRANDTECH Scientific Introduces the Transferpette® pro Micropipette: A New Twist on Comfort and Control