Companies Pursue Diagnostics that Mine the Microbiome

Tests so far typically screen for risky patterns that may augment traditional types of clinical data.

Written byAndrea Anderson
| 5 min read

Register for free to listen to this article
Listen with Speechify
0:00
5:00
Share

ISTOCK, TLFURRERIf we think of our bodies as walking, talking ecosystems, it stands to reason that microbial collections may change in response to the foods we eat and places we live. Similarly, disease-related shifts in the human environment are expected to influence our resident microbes, even if those microbes themselves don’t cause the changes.

Investigators and investors are increasingly banking on the possibility that microbes finding safe harbor in human habitats may be useful for detecting disease—from acute infections to chronic inflammatory conditions.

“It makes sense that the microbiome could be an indicator of lots of different things going on in the body,” said University of California, Davis, evolution and ecology researcher Jonathan Eisen, whose lab studies microbial contributions to ecosystem health. “The community of microbes is a pretty good readout of availability of carbon and nitrogen and activation of the immune system and oxygen levels and moisture levels and temperature. All of those things, pretty confidently, we know affect microbial communities,” he explained.

From that point of view, it’s not all that big a leap to think that ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here
February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies