Opinion: Stop Ignoring This Filament Crucial to Muscle Function
Opinion: Stop Ignoring This Filament Crucial to Muscle Function
Titin was discovered four decades ago, but some physiology textbooks fail to recognize the important role it plays in muscle contraction.
Opinion: Stop Ignoring This Filament Crucial to Muscle Function
Opinion: Stop Ignoring This Filament Crucial to Muscle Function

Titin was discovered four decades ago, but some physiology textbooks fail to recognize the important role it plays in muscle contraction.

Titin was discovered four decades ago, but some physiology textbooks fail to recognize the important role it plays in muscle contraction.

Critic at Large
Opinion: Learning from Immunotherapy’s Recent Failures
Opinion: Learning from Immunotherapy’s Recent Failures
Luis Felipe Campesato | Aug 1, 2018
The promise of immunotherapy is real. We now need to figure out how to maximize the number of patients the approach benefits.
Opinion: Understanding and Coping With Rising Publication Costs
Opinion: Understanding and Coping With Rising Publication Costs
M. Bishr Omary and Theodore S. Lawrence | Sep 1, 2017
As article processing charges top $5,000 at some research journals, authors and institutions have means of negotiating better deals or finding less expensive options.
Opinion: Address Taxonomic Skew
Opinion: Address Taxonomic Skew
Malcolm F. Rosenthal, Maydianne C.B. Andrade | May 30, 2017
The domination of model organisms and charismatic megafauna in the literature is a disservice to the life sciences.
Opinion: Why I Published in a Predatory Journal
Opinion: Why I Published in a Predatory Journal
John H. McCool | Apr 6, 2017
Our totally bogus case report swiftly passed muster, with only minor revisions requested.
Opinion: More Biomarkers Needed for Cancer Immunotherapy
Opinion: More Biomarkers Needed for Cancer Immunotherapy
David Fabrizio | Apr 1, 2017
Measuring PD-L1 levels was a great start. Now we need to quantify more protein biomarkers, assess the tumor mutational landscape, and examine immune cell signatures, too.
Opinion: Birds of a Feather?
Opinion: Birds of a Feather?
Geoffrey E. Hill | Mar 10, 2017
Taking into account the interaction of nuclear and mitochondrial genes in birds holds the promise of more objectively defining what constitutes a species.
Opinion: Improving FDA Evaluations Without Jeopardizing Safety and Efficacy
Opinion: Improving FDA Evaluations Without Jeopardizing Safety and Efficacy
John D. Loike and Jennifer Miller | Feb 1, 2017
What can be done to lower development costs and drug prices?
Opinion: Ethical Considerations of “Three-Parent” Babies
Opinion: Ethical Considerations of “Three-Parent” Babies
John D. Loike and Nancy Reame | Dec 22, 2016
Mitochondrial replacement therapy raises important societal and ethical concerns, but should be embraced for its utility in preventing disease.
Opinion: An Ethical Code for Conferences
Opinion: An Ethical Code for Conferences
Wolf B. Frommer | Dec 2, 2016
This fundamental form of scientific communication is threatened by modern recording technology and researchers who refuse to adhere to an age-old ethical code.