C-fos stained hippocampus following temporal interference stimulation
TSAI AND BOYDEN LABS
Deep brain stimulation can improve debilitating, treatment-resistant brain disorders but involves surgically implanting electrodes that often have to penetrate multiple layers of tissue before reaching their targets. In a mouse study published today (June 1) in the journal Cell, researchers devised a nonsurgical method in mice for stimulating regions buried beneath the brain’s cortex without perturbing the surrounding tissue.
“I just find the whole nature of it amazingly elegant,” says Helen Mayberg, a professor and neurologist at Emory University who was not involved in this work. “From the vantage point of deep brain stimulation, I look at this and say, how do we get from what I do to what they do?”
Doctors have shown deep brain stimulation can improve Parkinson’s disease, depression, and severe cases of obsessive-compulsive disorder in some patients and has ...