Skip to main content

Defying Dogma: Decentralized Translation in Neurons

To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.

Written byDanielle Gerhard, PhD
| 17 min read
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Register for free to listen to this article
Listen with Speechify
0:00
17:00

More than a century ago, the anatomist Santiago Ramón y Cajal unveiled his incredibly detailed drawings of neurons. From these, he posited that neurons were the main building blocks of the brain and that memories might be encoded in the connections between neurons.1 Since then, neuroscientists have been trying to answer how neurons and the networks they weave capture something so complex, so illusory, as a memory.

Our three-pound brains are home to nearly 100 billion neurons (almost equivalent to the number of stars in the milky way) that communicate across short and long distances, shaping our behavior and identities. Intercellular communication is not unique to neurons, but the sheer scale of their interactions distinguish neurons from other cells. “Neurons are in the business of interacting and connecting,” said Erin Schuman, a neuroscientist at the Max Planck Institute for Brain Research.

Neurons are in the business of interacting and connecting.

...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member?
Add The Scientist as a preferred source on Google

Add The Scientist as a preferred Google source to see more of our trusted coverage.

Meet the Author

  • Black and white photo of Danielle Gerhard

    Danielle is a Senior Editor at The Scientist. She earned her PhD in psychology and behavioral neuroscience from Yale University and completed a postdoctoral fellowship in neuroscience Weill Cornell Medicine. Her research explored the cellular and molecular mechanisms of stress and depression across development. She has served as editor-in-chief of the Yale Journal of Biology and Medicine, contributed stories to BioTechniques News and Drug Discovery News, and engaged in various science outreach initiatives across Connecticut and NYC.

    View Full Profile

Published In

<em>The Scientist </em>Fall 2023 cover
Fall 2023

Defying Dogma

To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.

Related Topics

The Scientist October Digest cover
October 2026

Antarctica’s Blood Falls Teems With Mysterious Microbial Life

Miles away from the closest ocean, marine microbes thrive in the red ice and mud around Blood Falls, offering clues to microbial adaptation and past climate events.

View this Issue
Evaluating Blood Biomarkers for Alzheimer’s Disease Staging

Evaluating Blood Biomarkers for Alzheimer’s Disease Staging

​Beckman Coulter
Find better biologics faster with Stunner and the AI Developability Workcell

Find better biologics faster with Stunner and the AI Developability Workcell

Unchained Labs
An image of microcentrifuge tubes arranged within colorful laboratory racks.

Choose clarity. Choose speed. Choose MyMass™

Refeyn
Characterizing LNP Heterogeneity With Super-Resolution Imaging

Characterizing LNP Heterogeneity With Super-Resolution Imaging

Oni

Products

Stellaromics Logo

Stellaromics Expands Pyxa Adoption as Instruments are Installed at Leading Research Institutions Across the U.S. and EuropeStellaromics, Inc., the leader in 3D

A monoclonal antibody surrounded by immune cells and red blood cells

CellRaft AIR: Find the Right Antibody-Producing Cells Faster

Cell Microsystems
Maxwell® Rapid ccfDNA Kit

Maxwell® Rapid ccfDNA Kit: Automated Purification of ccfDNA in Under 30 Minutes

Promega
Leica Biosystems, Tempus, and Paige logos side by side, marking the addition of Paige digital pathology AI tools to the Aperio AI Store.

Oncology Researchers Gain AI Cancer Tools in One Platform