illustration of a large purple molecular complex with a strand of orange RNA running through it and red strand emerging from it
Study Reveals Outsize Role of mRNA Region in Tuning Expression
A new method helps researchers uncover the rules of ribosome recruitment in yeast.
ABOVE: © ISTOCK.COM, SELVANEGRA
Study Reveals Outsize Role of mRNA Region in Tuning Expression
Study Reveals Outsize Role of mRNA Region in Tuning Expression

A new method helps researchers uncover the rules of ribosome recruitment in yeast.

A new method helps researchers uncover the rules of ribosome recruitment in yeast.

ABOVE: © ISTOCK.COM, SELVANEGRA

translation

Fruit flies in a vial
Accurate Protein Production Promotes Longevity
Ruth Williams | Sep 15, 2021
Worms, flies, and yeast live longer if the fidelity of their protein-making machinery is improved, a study shows.
A microscope image of a dinoflagellate.
Dinoflagellate Genome Structure Unlike Any Other Known
Amanda Heidt | May 10, 2021
The transcription of DNA drives the remarkably tidy organization of chromosomes in the dinoflagellate Symbiodinium microadriaticum.
The Scientist Speaks - Thieves on the Inside: Viral Control of Host Gene Expression
Niki Spahich, PhD | May 25, 2021
Britt Glaunsinger discusses how viruses steal from their hosts to take over cellular processes and promote their own survival.
How RNAs Called SINEUPs Upregulate Translation
Catherine Offord | Jan 1, 2021
The recently discovered long noncoding RNAs seem to boost the production of specific proteins in the cell by interacting with RNA-binding proteins, researchers find.
Infographic: Synthetases and the Evolution of Circulatory Systems
Amber Dance | Jun 1, 2020
Aminoacyl tRNA synthetases picked up new protein domains that participate in vasculature formation around the same time that organisms evolved key adaptations in the circulatory system.
Protein Synthesis Enzymes Have Evolved Additional Jobs
Amber Dance | Jun 1, 2020
Aminoacyl-tRNA synthetases, which help translate the genetic code into protein, also function in angiogenesis, fat metabolism, and more.
Paper Used in Creationist Teaching Retracted After 30 Years
Ashley Yeager | Nov 11, 2019
Criticism of the paper first surfaced in 1994, and its author was accused of scientific misconduct.
translation gene genetics ribosome enhancers knowable magazine
What Does It Look Like to “Turn On” a Gene?
Alla Katsnelson, Casey Rentz, Knowable Magazine | May 3, 2019
Only recently have scientists directly witnessed this most pivotal of events in biology, thanks to new technology that allows them to observe the process in living cells. It’s teaching them a lot.
Study: Ribosomes are Functionally Diverse
Diana Kwon | Jun 22, 2017
New research suggests that the cells’ protein factories have preferences for specific messenger RNAs they translate. 
Mouse Livers Grow and Shrink Daily
Abby Olena | May 4, 2017
Feeding-fasting rhythms and light-dark cycles direct regular changes in organ and cell size, as well as ribosome number and protein levels.
Noncoding RNA Helps Cells Recover from DNA Damage
Diana Kwon | May 1, 2017
Scientists discover transcripts from the same gene that can express both proteins and noncoding RNA.
 
Starvation Response Triggers Melanoma Invasion
Catherine Offord | Apr 1, 2017
Through similar mechanisms, amino acid depletion in culture and cytokine activity in the tumor microenvironment prompt cancer cells to metastasize.
Top Technical Advances 2016
Kerry Grens | Dec 15, 2016
The year’s most impressive achievements include methods to watch translation in cells, trace cell fates, avoid mitochondrial mutations, edit DNA, and build antibiotics from scratch.
How to Track Translation in Living Cells
Ruth Williams | Oct 1, 2016
Four independent research groups develop techniques for visualizing peptide production in living cells.
Protozoans Found With No Dedicated Stop Codons
Karen Zusi | Oct 1, 2016
Some ciliates use the same trio of nucleotides to code for an amino acid and to stop translation.
Ciliates Are Genetic-Code Deviants
Karen Zusi | Sep 30, 2016
Traditional stop codons have a double meaning in the protozoans' mRNA, sometimes calling for an amino acid during translation.
Scientists Catch Translation in the Act
Ruth Williams | Sep 30, 2016
Newly developed techniques from four different groups rely on the same basic steps to track translation in live cells.
Wanted: Transcriptional Regulators
Ruth Williams | Aug 1, 2016
Researchers have designed a screen to find unique molecules, called riboswitches, that determine whether transcription will proceed.
Riboswitch Screen
Ruth Williams | Jul 31, 2016
A newly developed method detects regulators of bacterial transcription called riboswitches.