Early Detection of Dementia with Smart Devices

Digital biomarkers of cognitive decline could alert us to the early stages of dementia before irreversible damage occurs.

Written byRachael Moeller Gorman
| 17 min read

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Three years ago, Eli Lilly, Apple, and California-based health and measurement company Evidation Health came together to ask a new kind of research question: Can we identify cognitive impairment by analyzing the many types of digital data people inadvertently generate in their everyday lives?

For 12 weeks in 2018, more than 100 people with varying states of cognitive decline—or none at all—used an iPhone, an Apple Watch, an iPad pro with a smart keyboard, and a Beddit sleep monitoring device. Each of these devices contains various sensors such as gyroscopes, pedometers, accelerometers, heart rate monitors, and sleep sensors. The iPad also administered language and motor control tests on a biweekly basis. Throughout the study period, participants talked, slept, worked, cleaned, and socialized as their digital biomarker data streams flowed to a cloud-based server viewed by researchers at the study headquarters at Evidation in San Mateo.

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Meet the Author

  • After earning a bachelor’s degree in biology and neuroscience from Williams College, Rachael spent two years studying the tiny C. elegans worm as a lab tech at Massachusetts General Hospital/Harvard University. She then returned to school to get a master’s degree in environmental studies from Brown University, and subsequently worked as an intern at Scientific AmericanDiscover magazine, and the Annals of Improbable Research, the originators of the yearly Ig Nobel prizes. She now freelances for both scientific and lay publications, and loves telling the stories behind the science. Find her at rachaelgorman.com or on Instagram @rachaelmoellergorman.

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