Fraudulent Paper Pulled

Nature retracts a study six years after an investigation found that the protein structures it reported were fabricated.

Written byBob Grant
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WIKIMEDIA, NIKLAS BILDHAUERA paper on protein structures published in Nature in 2006 was retracted by the journal’s publisher yesterday (January 4), six years after an investigation conducted by the lead author’s institution found that the structures were fabricated. Neither Nature nor the paper’s authors have fully explained why it took so long to retract the study. “This is a pretty old story, I don’t know why Nature took so long,” coauthor Narayana Sthanam from the University of Alabama at Birmingham (UAB) told Retraction Watch. “Nature asked us maybe two months back, do I have any comment or objection for retracting.”

The retraction notice posted by Nature indicates that two of the paper’s six authors did not agree to voluntarily retract the paper; three agreed to the retraction, while one author did not respond. One of the coauthors who did not agree with the retraction, former UAB researcher M. Krishna Murthy, was found “solely responsible for the fraudulent data” by the UAB investigation.

The retracted Nature paper described the crystal structure of a protein called C3b, which plays a role in immune response pathways. The manuscript raised red flags soon after it was published, as it contradicted other published models. UAB launched an investigation into the discrepancies in 2006, and published its findings concerning misconduct on the part of Murthy in 2009. According to Retraction Watch, ...

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  • From 2017 to 2022, Bob Grant was Editor in Chief of The Scientist, where he started in 2007 as a Staff Writer. Before joining the team, he worked as a reporter at Audubon and earned a master’s degree in science journalism from New York University. In his previous life, he pursued a career in science, getting a bachelor’s degree in wildlife biology from Montana State University and a master’s degree in marine biology from the College of Charleston in South Carolina. Bob edited Reading Frames and other sections of the magazine.

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