Hormones May Contribute to Asymmetrical Effects of Brain Injury

Researchers studying rats claim to have found a novel connection between damage on one side of the brain and problems with the posture or movement of limbs on the opposite side of the body.

Written byCatherine Offord
| 4 min read
Illustrated rat

Register for free to listen to this article
Listen with Speechify
0:00
4:00
Share

ABOVE: ADAPTED FROM GIL COSTA (CC BY 4.0) AND A PHOTOGRAPHIC REPRODUCTION OF DE SPORTLIEDEN BY KAZIMIR MALEVICH

Injury to one side of the brain can cause abnormalities in posture or movement on the opposite side of the body. These effects, which are sometimes seen in people who have suffered a stroke or head trauma, have typically been attributed to neural pathways that link the right side of the brain to spinal cord neurons controlling muscles on the left side of the body, and vice versa.

But in a new study on rats that had their spinal cords severed, researchers claim to have discovered another, parallel pathway that triggers opposite-side effects following brain injury and might instead operate via hormones circulating in the blood. The work was published last month (August 10) in eLife.

The findings are “interesting and surprising,” says S. Thomas Carmichael, a neurologist at the University of ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Related Topics

Meet the Author

  • After undergraduate research with spiders at the University of Oxford and graduate research with ants at Princeton University, Catherine left arthropods and academia to become a science journalist. She has worked in various guises at The Scientist since 2016. As Senior Editor, she wrote articles for the online and print publications, and edited the magazine’s Notebook, Careers, and Bio Business sections. She reports on subjects ranging from cellular and molecular biology to research misconduct and science policy. Find more of her work at her website.

    View Full Profile
Share
Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.
January 2026, Issue 1

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

View this Issue
Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

Unchained Labs
Graphic of three DNA helices in various colors

An Automated DNA-to-Data Framework for Production-Scale Sequencing

illumina
Exploring Cellular Organization with Spatial Proteomics

Exploring Cellular Organization with Spatial Proteomics

Abstract illustration of spheres with multiple layers, representing endoderm, ectoderm, and mesoderm derived organoids

Organoid Origins and How to Grow Them

Thermo Fisher Logo

Products

Brandtech Logo

BRANDTECH Scientific Introduces the Transferpette® pro Micropipette: A New Twist on Comfort and Control

Biotium Logo

Biotium Launches GlycoLiner™ Cell Surface Glycoprotein Labeling Kits for Rapid and Selective Cell Surface Imaging

Colorful abstract spiral dot pattern on a black background

Thermo Scientific X and S Series General Purpose Centrifuges

Thermo Fisher Logo
Abstract background with red and blue laser lights

VANTAstar Flexible microplate reader with simplified workflows

BMG LABTECH