Cells in yellow are making new ribosomes, which is an important process for cell growth and proliferation.

A study published in Nature Communications reports that cells that increase the production of ribosomes when the cell-cycle is paused go through the epithelial-to-mesenchymal transition, allowing them to begin to migrate through the body. The authors suggest that this phenomenon is linked with cancer progression and how cancerous cells become metastatic.

V. Prakash et al., “Ribosome biogenesis during cell cycle arrest fuels EMT in development and disease,” Nature Communications, doi:10.1038/s41467-019-10100-8, 2019.

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