Infographic: Microbiome-Driven Adaptations in Animals

Researchers are using experiments and observational studies to look for host genetic variation that could be partly determined by the gut microbiota.

Written byCatherine Offord
| 2 min read

Register for free to listen to this article
Listen with Speechify
0:00
2:00
Share

ABOVE: © MICHELLE KONDRICH

Animals harbor vast numbers of microbes in their guts, but the effect of this community on the evolutionary trajectories of the hosts is unclear. Researchers are now using a combination of experiments and observational studies to look for signs of microbiome-driven host adaptation.

Researchers at the University of Pennsylvania split a large outbred population of fruit flies (Drosophila melanogaster) into 14 groups of 20 individuals and put each group on a peach tree enclosed with a mesh cage. Each population was given Lactobacillus-laced food (left), Acetobacter-laced food (right), or food with no bacterial addition (not shown). After five generations, the team collected the flies for genomic sequencing and found that the groups differed depending on the food they’d been given. (Graphic illustrates one possible scenario for variation at a single locus.) Some of the observed changes in allele frequencies matched variation seen in wild fruit fly ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Related Topics

Meet the Author

  • After undergraduate research with spiders at the University of Oxford and graduate research with ants at Princeton University, Catherine left arthropods and academia to become a science journalist. She has worked in various guises at The Scientist since 2016. As Senior Editor, she wrote articles for the online and print publications, and edited the magazine’s Notebook, Careers, and Bio Business sections. She reports on subjects ranging from cellular and molecular biology to research misconduct and science policy. Find more of her work at her website.

    View Full Profile

Published In

July 2021

Bacteria-Guided Evolution

Animals' adaptive changes may be influenced by microbes within

Share
February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies