It's a Cell-Eat-Cell World

For more than 100 years, pathologists have observed cancer cells engulfing other live cells, but scientists are only now beginning to understand how it happens and what it means for tumorigenesis.

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CORBIS, LAUGHTING STOCK

It was a late night in 1984, and graduate student Xiaoning Wang was all alone in the lab. At First Military Medical University (now Southern Medical University) in Guangzhou, China, he was working at the lab’s only camera-equipped microscope, under a wooden hood constructed by his advisor, using a hair dryer to keep a cell culture of murine sarcoma cells at 37°C—mouse (and human) body temperature. He’d been doing the same thing nearly every night for the past month, hoping to capture on film what he had witnessed just a few weeks earlier—a tumor cell engulfing a live natural killer (NK) cell, a lymphocyte of the innate immune system and a major player in tumor suppression. After many sleepless nights, he had started to worry ...

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Meet the Author

  • Jef Akst

    Jef Akst was managing editor of The Scientist, where she started as an intern in 2009 after receiving a master’s degree from Indiana University in April 2009 studying the mating behavior of seahorses.

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