The Challenge of Using CRISPR to Knock In Genes
The Challenge of Using CRISPR to Knock In Genes
Researchers are developing an array of techniques for accurately and efficiently inserting genes into DNA.
The Challenge of Using CRISPR to Knock In Genes
The Challenge of Using CRISPR to Knock In Genes

Researchers are developing an array of techniques for accurately and efficiently inserting genes into DNA.

Researchers are developing an array of techniques for accurately and efficiently inserting genes into DNA.

Lab Tools
Mapping the Cellular Social Network of Proteins
Mapping the Cellular Social Network of Proteins
Melissae Fellet | Feb 1, 2019
Three techniques capture data on numerous protein interactions in plants, mice, and human cells.
Researchers Engineer Epigenome Editors to Study How Gene Expression Affects Disease
Researchers Engineer Epigenome Editors to Study How Gene Expression Affects Disease
Ashley Yeager | Jan 1, 2019
Using CRISPR and other tools, scientists are modifying DNA methylation, histone marks, and other modifiers of gene expression to understand how they affect health and disease.
Imaging Chromatin to Deduce Function from Form
Imaging Chromatin to Deduce Function from Form
Marissa Fessenden | Dec 1, 2018
Researchers describe their tools for probing how the physical shape of the genome affects genes’ function.
Using Temperature-Sensitive Channels to Study Neural Circuitry
Using Temperature-Sensitive Channels to Study Neural Circuitry
Devika G. Bansal | Nov 1, 2018
Meet the researchers building a thermogenetic toolbox.
Integrating Multiple -Omics in Individual CellsIntegrating Multiple -Omics in Individual CellsIntegrating Multiple -Omics in Individual Cells
Integrating Multiple -Omics in Individual Cells
Sandeep Ravindran | Oct 1, 2018
New techniques combine DNA, RNA, and protein information from single cells.
Speeding Up Stem Cell Growth
Speeding Up Stem Cell Growth
Amber Dance | Sep 1, 2018
Scientists fiddle with formulas to boost the growth of their stem cell cultures.
How to Track Metabolites in Tissues Using NMR
How to Track Metabolites in Tissues Using NMR
Katherine Bourzac | Aug 1, 2018
Whether it’s aligning software or prepping samples, researchers share their tips for studying the metabolome with this underused approach.
How to Calculate Mutation Rate for Evolutionary Biology
How to Calculate Mutation Rate for Evolutionary Biology
Amber Dance | Jul 1, 2018
Four ways to study mutation rate, a crucial statistic in studies of evolution
Using Mimics to Get Around Antibodies’  Limitations
Using Mimics to Get Around Antibodies’ Limitations
Devika G. Bansal | Jun 1, 2018
Synthetic and natural alternatives to traditional antibodies offer more control, specificity, and reproducibility.