Lab Tools

Organisms with unusual genomes are helping scientists investigate gene regulation, evolution, and development.

Researchers are devising ways to prevent viral vectors carrying gene therapies from triggering an immune response.

New ways to search for druggable RNAs and matching small molecules

Researchers are using artificial intelligence to identify known and novel resistance genes.

Researchers describe ways to study how cancer cells evade therapies that harness the immune system.

Researchers are developing an array of techniques for accurately and efficiently inserting genes into DNA.

Three techniques capture data on numerous protein interactions in plants, mice, and human cells.

Using CRISPR and other tools, scientists are modifying DNA methylation, histone marks, and other modifiers of gene expression to understand how they affect health and disease.

Researchers describe their tools for probing how the physical shape of the genome affects genes’ function.

Meet the researchers building a thermogenetic toolbox.

New techniques combine DNA, RNA, and protein information from single cells.

Scientists fiddle with formulas to boost the growth of their stem cell cultures.

Whether it’s aligning software or prepping samples, researchers share their tips for studying the metabolome with this underused approach.

Four ways to study mutation rate, a crucial statistic in studies of evolution

Synthetic and natural alternatives to traditional antibodies offer more control, specificity, and reproducibility. 

Software that can separate signals from noise brings neuroscientists a step closer to understanding neurons’ patterns of communication.

Tools for studying how cancer spreads

Researchers have developed a variety of techniques to detect when CRISPR misses the mark.

Researchers are using souped-up mass spectrometry to localize proteins within brain cells.