Cannabis on Board

2018 closed with hubbub surrounding the purported birth of babies whose genomes had been edited using CRISPR. What will 2019 hold for CRISPR’s use in humans?

The sturgeon restoration study’s outcome won’t be known for decades.

Transposon mutagenesis give scientists a rare look at the most important interactions within microbial communities.

In addition to detecting unseen organisms in the ocean, studies of environmental DNA can shed light on the genetic structure of marine populations.

Large-scale genomic studies of anorexia and bulimia are turning up clues about the conditions’ development and persistence.

Meet some of the people featured in the January 2019 issue of The Scientist.

Researchers repurpose the CRISPR machinery to turn whole classes of transposable elements on or off.

Amputation of one limb triggers a rapid electric response that reflects the injury in the opposite one, researchers find.

Inhibiting nerve cells that produce the neurotransmitter made it harder for baby mice to recover from bouts of slowed breathing.

The energy-producing organelles also send out parcels with antimicrobial compounds to help destroy pathogen invaders in macrophages.

By tying together his understanding of the microbiome and nucleic acids, the UPenn immunologist is decoding the underlying causes of inflammation and disease.

Scientists are working to maximize the benefits and minimize the costs of sharing.

By uncovering novel properties of a unique population of T cells, the Scripps Research Institute immunologist has helped to redefine the immune cells, uncovering their role in wound healing.

Using CRISPR and other tools, scientists are modifying DNA methylation, histone marks, and other modifiers of gene expression to understand how they affect health and disease.

As advanced as humans are, we still don’t have a handle on how to tame our response to a night of drinking.

Charles R. Knight’s illustrations shaped the public’s view of prehistoric life.

Researchers repurpose the CRISPR machinery to turn whole classes of transposable elements on or off.

Human endogenous retroviruses that colonized vertebrate DNA millions of years ago have long been dismissed as junk DNA, but researchers now know that they may play important roles in cancer, neurodegeneration, and other ailments.

Urban environments are driving genetic changes in resident species through multiple mechanisms, from establishing gene flow barriers to exerting novel selection pressures.

Rodent and human studies have revealed a multitude of effects starting during gestation and lasting into adulthood.

Researchers have uncovered a mechanism whereby macrophages employ their energy-generating organelles to aid in bacterial killing.

Take a break from the bench to puzzle and peruse.