Mammoth Proteome Described

Eschewing potentially degraded DNA as a source, researchers look instead at the proteome of ancient species.

| 1 min read

Register for free to listen to this article
Listen with Speechify
0:00
1:00
Share

Woolly MammothWIKIMEDIA COMMONS, TRACY O

An international team of researchers have uncovered 126 proteins from the femur of a prehistoric woolly mammoth, paving the way for the proteomic exploration of other long-dead organisms.

The researchers used mass spectrometry and refined the sample preparation techniques in order to ensure that the proteins analyzed were indeed from the mammoth, and not a rubber protein from a researcher’s glove, for example, reported Nature. Analysis yielded blood and extracellular matrix proteins, as well as albumin, which is sufficiently variable between species to be used to study evolutionary relationships across the animal kingdom.

“Now we can go back in time and see what we can detect in older samples,” first author Enrico Cappellini from the Centre for GeoGenetics at the Natural History Museum of Denmark ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Keywords

Meet the Author

  • Edyta Zielinska

    This person does not yet have a bio.
Share
Image of a woman in a microbiology lab whose hair is caught on fire from a Bunsen burner.
April 1, 2025, Issue 1

Bunsen Burners and Bad Hair Days

Lab safety rules dictate that one must tie back long hair. Rosemarie Hansen learned the hard way when an open flame turned her locks into a lesson.

View this Issue
Characterizing Immune Memory to COVID-19 Vaccination

Characterizing Immune Memory to COVID-19 Vaccination

10X Genomics
Pairing Protein Engineering and Cellular Assays

Pairing Protein Engineering and Cellular Assays

Lonza
Faster Fluid Measurements for Formulation Development

Meet Honeybun and Breeze Through Viscometry in Formulation Development

Unchained Labs
Conceptual image of biochemical laboratory sample preparation showing glassware and chemical formulas in the foreground and a scientist holding a pipette in the background.

Taking the Guesswork Out of Quality Control Standards

sartorius logo

Products

Metrion Biosciences Logo

Metrion Biosciences launches NaV1.9 high-throughput screening assay to strengthen screening portfolio and advance research on new medicines for pain

Biotium Logo

Biotium Unveils New Assay Kit with Exceptional RNase Detection Sensitivity

Atelerix

Atelerix signs exclusive agreement with MineBio to establish distribution channel for non-cryogenic cell preservation solutions in China

Green Cooling

Thermo Scientific™ Centrifuges with GreenCool Technology

Thermo Fisher Logo