Mice Learn Faster with Human Glia

Mice with human brain cells showed enhanced synaptic plasticity and learning, suggesting glia may be key to our cognitive prowess.

Written byDan Cossins
| 3 min read

Register for free to listen to this article
Listen with Speechify
0:00
3:00
Share

WIKIMEDIA, BRUNO PASCALMice that received transplants of human glial progenitor cells learned much more quickly than normal mice, according to a study published today (March 7) in Cell Stem Cell. The findings support the theory that glial cells made a significant contribution to the evolution of our own enhanced cognitive abilities.

“This work is very exciting and surprising because it demonstrates that there may be something special about human glial progenitor cells that contribute to the amazing complexity and computational abilities of the human brain,” said Robert Malenka, a neuroscientist at Stanford University who was not involved in the study, in an email to The Scientist.

For many years, glia cells, non-neuronal cells present in the same numbers as neurons in the brain, were thought to play only a supporting role, providing structure, insulation, and nutrients for neurons. But in the past 20 years it has become clear that glia also participate in the transmission of electrical signals. Specifically, astrocytes—a type of glial cell with thousands of tendrils that reach and encase synapses—can modulate signals passing ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Related Topics

Meet the Author

Share
Image of a woman with her hands across her stomach. She has a look of discomfort on her face. There is a blown up image of her stomach next to her and it has colorful butterflies and gut bacteria all swarming within the gut.
November 2025, Issue 1

Why Do We Feel Butterflies in the Stomach?

These fluttering sensations are the brain’s reaction to certain emotions, which can be amplified or soothed by the gut’s own “bugs".

View this Issue
Olga Anczukow and Ryan Englander discuss how transcriptome splicing affects immune system function in lung cancer.

Long-Read RNA Sequencing Reveals a Regulatory Role for Splicing in Immunotherapy Responses

Pacific Biosciences logo
Research Roundtable: The Evolving World of Spatial Biology

Research Roundtable: The Evolving World of Spatial Biology

Conceptual cartoon image of gene editing technology

Exploring the State of the Art in Gene Editing Techniques

Bio-Rad
Conceptual image of a doctor holding a brain puzzle, representing Alzheimer's disease diagnosis.

Simplifying Early Alzheimer’s Disease Diagnosis with Blood Testing

fujirebio logo

Products

Eppendorf Logo

Research on rewiring neural circuit in fruit flies wins 2025 Eppendorf & Science Prize

Evident Logo

EVIDENT's New FLUOVIEW FV5000 Redefines the Boundaries of Confocal and Multiphoton Imaging

Evident Logo

EVIDENT Launches Sixth Annual Image of the Year Contest

10x Genomics Logo

10x Genomics Launches the Next Generation of Chromium Flex to Empower Scientists to Massively Scale Single Cell Research