Microflora for Hire

The guts of cows and termites harbor microbes that are renowned complex-carbohydrate digesters, but the human gastrointestinal tract has flora that just might measure up.

| 4 min read

Register for free to listen to this article
Listen with Speechify
0:00
4:00
Share

GUT BUGS: Bacteroides species crowd the human gut, where they degrade the hemicelluloses that would otherwise go undigested.CDC/DR. V.R. DOWELL, JR. (PHIL #3087), 1972/WIKIPEDIA

In the midst of his graduate training at the University of Illinois at Urbana-Champaign, Dylan Dodd spent a good chunk of time examining bacteria from cow stomachs. He characterized a suite of enzymes that allow one species, Prevotella bryantii, to break down the polysaccharide xylan, a major constituent of plant cell walls.

Along with his adviser, microbiologist and animal scientist Isaac Cann, Dodd was “prospecting” for enzymes that might be conscripted for biofuel production. Searching for related enzymes in other organisms, he uncovered genes from several species of Bacteroides—common microbial inhabitants of the human colon (J Bio Chem, 285:30261-73, 2010).

Even though Bacteroides and Prevotella belong to the same phylum, the similarity was unexpected, Dodd says: “Although they both [inhabit] gastrointestinal environments, they are rather ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Keywords

Meet the Author

  • Molly Sharlach

    This person does not yet have a bio.

Published In

Share
May digest 2025 cover
May 2025, Issue 1

Study Confirms Safety of Genetically Modified T Cells

A long-term study of nearly 800 patients demonstrated a strong safety profile for T cells engineered with viral vectors.

View this Issue
iStock

TaqMan Probe & Assays: Unveil What's Possible Together

Thermo Fisher Logo
Meet Aunty and Tackle Protein Stability Questions in Research and Development

Meet Aunty and Tackle Protein Stability Questions in Research and Development

Unchained Labs
Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Bio-Rad
How technology makes PCR instruments easier to use.

Making Real-Time PCR More Straightforward

Thermo Fisher Logo

Products

The Scientist Placeholder Image

Biotium Launches New Phalloidin Conjugates with Extended F-actin Staining Stability for Greater Imaging Flexibility

Leica Microsystems Logo

Latest AI software simplifies image analysis and speeds up insights for scientists

BioSkryb Genomics Logo

BioSkryb Genomics and Tecan introduce a single-cell multiomics workflow for sequencing-ready libraries in under ten hours

iStock

Agilent BioTek Cytation C10 Confocal Imaging Reader

agilent technologies logo