Neural Circuit of Parental Behavior Mapped in Mice

This is the first time the precise brain cells and their connections controlling a complex behavior have been worked out.

Written byJim Daley
| 3 min read

Register for free to listen to this article
Listen with Speechify
0:00
3:00
Share

In the mouse brain, a cluster of neurons (red) within the medial preoptic area acts as a parenting control hub, orchestrating behaviors such as grooming and interacting with pups. DULAC LAB/HHMI/HARVARD

Whether in humans or in mice, parenting entails a suite of behaviors, including grooming, feeding, and protecting young, but the neural systems that guide these activities remain poorly understood. Researchers have now made some headway, having deconstructed some of the neural circuitry responsible for this complex behavior, which the authors say is the first such map of its kind. Yesterday (April 11) in Nature they report that the neurons that govern parenting in mice’s brains are organized into distinct pools originating in the hypothalamus, with each department communicating with any of 20 other regions in the brain and directing a specific parenting activity.

“This is a very ambitious study,” says Robert Bridges, a neuroscientist at Tufts University who did not participate in the work. The ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Related Topics

Meet the Author

Share
Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.
January 2026

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

Unchained Labs

Products

Sino Biological Logo

Sino Biological's Launch of SwiftFluo® TR-FRET Kits Pioneers a New Era in High-Throughout Kinase Inhibitor Screening

SPT Labtech Logo

SPT Labtech enables automated Twist Bioscience NGS library preparation workflows on SPT's firefly platform

nuclera logo

Nuclera eProtein Discovery System installed at leading Universities in Taiwan

Brandtech Logo

BRANDTECH Scientific Introduces the Transferpette® pro Micropipette: A New Twist on Comfort and Control