Opinion: A TB Vaccine Blueprint

With 12 new tuberculosis vaccines in clinical development, a plan is needed to introduce the most effective ones throughout the world.

Written byMichael J. Brennan and Jelle Thole
| 3 min read

Register for free to listen to this article
Listen with Speechify
0:00
3:00
Share

Skin test for tuberculosisWIKIMEDIA COMMONS, CDC PUBLIC HEALTH IMAGE LIBRARY

Thousands of children, women, and men die each day from tuberculosis (TB). It is the deadliest infectious disease after HIV, and increasing drug resistance threatens to wipe out medicine’s best weapons against the TB bacterium. New tools to control the disease are needed to bring this global epidemic to a halt and prevent millions from suffering. To this end, we and others drafted “Tuberculosis Vaccines: A Strategic Blueprint for the Next Decade,” which lays out a plan for solving the current problems caused by this ancient disease using one of the most effective and affordable public health tools modern science offers for infectious diseases: vaccines.

The only vaccine currently available for TB was developed more than 90 years ago and is ineffective against the spread ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Related Topics

Meet the Author

Share
Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.
January 2026, Issue 1

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

View this Issue
Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

Unchained Labs
Graphic of three DNA helices in various colors

An Automated DNA-to-Data Framework for Production-Scale Sequencing

illumina
Exploring Cellular Organization with Spatial Proteomics

Exploring Cellular Organization with Spatial Proteomics

Abstract illustration of spheres with multiple layers, representing endoderm, ectoderm, and mesoderm derived organoids

Organoid Origins and How to Grow Them

Thermo Fisher Logo

Products

Brandtech Logo

BRANDTECH Scientific Introduces the Transferpette® pro Micropipette: A New Twist on Comfort and Control

Biotium Logo

Biotium Launches GlycoLiner™ Cell Surface Glycoprotein Labeling Kits for Rapid and Selective Cell Surface Imaging

Colorful abstract spiral dot pattern on a black background

Thermo Scientific X and S Series General Purpose Centrifuges

Thermo Fisher Logo
Abstract background with red and blue laser lights

VANTAstar Flexible microplate reader with simplified workflows

BMG LABTECH