Skip to main content

Opinion: Missing Methods

A lack of methodological detail in the published literature threatens the foundation of scientific discourse.

Written byIrwin H. Gelman
| 4 min read

Register for free to listen to this article
Listen with Speechify
0:00
4:00

ISTOCKPHOTO, LORAN NICOLAS

All of us know the apocryphal tale where the mother-in-law “shares” a secret family recipe, but as much as you try, the cookies never taste the same as Mama’s. Of course, Mama’s withholding of the full recipe is a move to sustain her generational authority, perhaps a last grasp for her son’s affection, and definitely, a chance to show up that good-for-nothing daughter-in-law. This is my current fear about science: that soon, we will no longer be able to make cookies the way Mama did.

A pillar of our scientific system is that “true” findings will be validated when other labs repeat experiments, and thus, there is almost a sacred obligation to clearly explain our technical details in the Methods or Procedures sections of our ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member?
Add The Scientist as a preferred source on Google

Add The Scientist as a preferred Google source to see more of our trusted coverage.

Meet the Author

Related Topics

Related articles background image
The Scientist Digest cover September 2026
September 2026

Multiplex Microscopy Becomes Easier with Encoded Antibodies

A new system that enables researchers to uniquely tag monoclonal antibodies for use in microscopy could help simplify complex imaging studies.

View this Issue
Essential Genes Are Dominantly Activated by Single Transcription Factors

Essential Genes Are Dominantly Activated by Single Transcription Factors

EpiCypher Logo
Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Alamar Biosciences logo
Engineering CAR-Neutrophils In Vivo to Target Glioblastoma

Engineering CAR-Neutrophils In Vivo to Target Glioblastoma

Miltenyi
Best Practices for qPCR Assay Design and Optimization

Best Practices for qPCR Assay Design and Optimization

Bio-Rad

Products

Closeup image of a multi channel pipette dispensing pink liquid into a 96-well plate.

The ASSIST PLUS pipetting robot for affordable workflow automation

Integra Logo
Single cells in suspension

Rapidly isolate primary cells and make uniform single-cell suspensions with Corning® Cell Strainers

Corning logo
Abstract image representing cell membranes linked together.

CellBrite® Steady Membrane Stain: Cell surface staining built for real-time imaging

Biotium
sino biological logo

Monod Bio Licenses AI-designed Protein Technologies to SignalChem Biotech for Custom Discovery Assays