Really Bad Breath

Tobacco hornworms release puffs of nicotine that deter some predators.

Written byAbby Olena, PhD
| 2 min read

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Nicotine is poisonous to most animals, but not to the tobacco hornworm (Manduca sexta). Now, researchers have shown that cytochrome P450 6B46 (CYP6B46)—a hornworm gene that helps metabolize nicotine—sends a small percentage of the nicotine consumed to the larva’s hemolymph, from which it is released into the air around the caterpillar and deters some predators in a kind of “toxic halitosis.” Their work was published in Proceedings of the National Academy of Sciences this week (December 30).

“It’s really a story about how an insect that eats a plant co-opts the plant for its own defense,” coauthor Ian Baldwin of the Max Planck Institute for Chemical Ecology in Germany told Live Science.

Baldwin’s team previously showed that predators were more likely to feed on hornworm ...

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Meet the Author

  • abby olena

    As a freelancer for The Scientist, Abby reports on new developments in life science for the website. She has a PhD from Vanderbilt University and got her start in science journalism as the Chicago Tribune’s AAAS Mass Media Fellow in 2013. Following a stint as an intern for The Scientist, Abby was a postdoc in science communication at Duke University, where she developed and taught courses to help scientists share their research. In addition to her work as a science journalist, she leads science writing and communication workshops and co-produces a conversational podcast. She is based in Alabama.  

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