Researchers Create Pathogen-Sensing Face Mask

The masks contain freeze-dried, cell-free biosensors, enabling them to detect pathogens including SARS-CoV-2.

Written byAnnie Melchor
| 5 min read
photograph of a woman wearing a face mask embedded with SARS-CoV-2 sensors

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ABOVE: Prototype of a SARS-CoV-2–detecting mask
WYSS INSTITUTE AT HARVARD UNIVERSITY

A face mask that both protects against respiratory pathogens and tests for SARS-CoV-2 as accurately as a lab test? It sounds like science fiction.

But in a study published June 28 in Nature Biotechnology, a group led by researchers at Harvard’s Wyss Institute and MIT incorporates biosensors into fabric, creating a SARS-CoV-2–sensing face mask and a jacket that can detect antibiotic-resistant bacteria.

As far as the authors know, it’s the first demonstration of textile fibers using cell-free systems “that have been engineered to harness the core sensing mechanisms of cellular biological systems,” says coauthor Luis Soenksen of MIT.

It’s not the first time researchers have incorporated biological components into wearable sensors. In a quest to make devices such as stick-on tattoos that sense small molecules on the skin or running gear that opens ventilating flaps when exposed to sweat, scientists ...

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    Stephanie "Annie" Melchor got her PhD from the University of Virginia in 2020, studying how the immune response to the parasite Toxoplasma gondii leads to muscle wasting and tissue scarring in mice. While she is still an ardent immunology fangirl, she left the bench to become a science writer and received her master’s degree in science communication from the University of California, Santa Cruz, in 2021. You can check out more of her work here.

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