Side-by-Side Comparisons of Important SARS-CoV-2 Variants

Here’s our brief guide to the most noteworthy mutations in the novel coronavirus.

Written byKatarina Zimmer
| 3 min read
nextstrain sars-cov-2 variant tracking covid-19 coronavirus pandemic n510y 501Y.V2 b.1.1.7 B.1.351 e484k k417n p.1 virology

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ABOVE: Since its spillover into the human population in late 2019, SARS-CoV-2 has diversified into many clades and variants.
NEXTSTRAIN.ORG

A range of SARS-CoV-2 variants has emerged across the world since the COVID-19 pandemic began. Most attention has been on fast-spreading variants recently identified in the UK, South Africa, and Brazil. Scientists suspect that the variants’ particular patterns of mutations have the potential to affect their transmissibility, virulence, and/or ability to evade parts of the immune system. The latter could make people with vaccine-induced or natural immunity to SARS-CoV-2 vulnerable to becoming reinfected with novel variants, and these possible effects remain under investigation.

There are a handful of other variants—typically with fewer eye-catching mutations—that researchers are also keeping a close watch on, notes molecular epidemiologist Emma Hodcroft of the University of Bern in Switzerland. Making matters confusing, scientists can’t agree on a standardized naming system for new variants, causing what one ...

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Meet the Author

  • katya katarina zimmer

    After a year teaching an algorithm to differentiate between the echolocation calls of different bat species, Katarina decided she was simply too greedy to focus on one field of science and wanted to write about all of them. Following an internship with The Scientist in 2017, she’s been happily freelancing for a number of publications, covering everything from climate change to oncology. Katarina is a news correspondent for The Scientist and contributes occasional features to the magazine. Find her on Twitter @katarinazimmer and read her work on her website.

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