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A DNA sequence represented by its base letters.
Measuring the Genome and Methylome at Single Base Resolution
Researchers can build models to predict gene expression by detecting and differentiating between cytosine methylation and hydroxymethylation marks in the genome.
Measuring the Genome and Methylome at Single Base Resolution
Measuring the Genome and Methylome at Single Base Resolution

Researchers can build models to predict gene expression by detecting and differentiating between cytosine methylation and hydroxymethylation marks in the genome.

Researchers can build models to predict gene expression by detecting and differentiating between cytosine methylation and hydroxymethylation marks in the genome.

5-methylcytosine

Opinion: The New Frontiers of Epigenetics
John D. Loike | Nov 12, 2018 | 3 min read
Newly developed techniques could propel a field already advancing rapidly to complement modern medicine.
The Role of DNA Base Modifications
Skirmantas Kriaucionis | Sep 1, 2017 | 10+ min read
Researchers are just beginning to scratch the surface of how several newly recognized epigenetic changes function in the genome.
Infographic: The Various Forms of Methylated DNA
Skirmantas Kriaucionis | Aug 31, 2017 | 1 min read
To expand the basic nucleotide alphabet, many species modify their DNA with epigenetic marks.
Estimating Epigenetic Mutation Rates
Jenny Rood | May 11, 2015 | 2 min read
Generation-spanning maps of Arabidopsis thaliana DNA methylation allow researchers to compute how quickly epigenetic marks appear and disappear in the plant’s genome.
Unmasking Secret Identities
Kate Yandell | Feb 1, 2014 | 9 min read
A tour of techniques for measuring DNA hydroxymethylation
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