Small group of Scimitar-horned oryx
Tool Identifies Likely Reservoir Species for SARS-CoV-2
Researchers used sequencing data and phenotypic traits to predict which of 5,400 species were most likely to be susceptible to contracting and spreading the virus back to humans.
ABOVE: © ISTOCK.COM, CONTOURPM
Tool Identifies Likely Reservoir Species for SARS-CoV-2
Tool Identifies Likely Reservoir Species for SARS-CoV-2

Researchers used sequencing data and phenotypic traits to predict which of 5,400 species were most likely to be susceptible to contracting and spreading the virus back to humans.

Researchers used sequencing data and phenotypic traits to predict which of 5,400 species were most likely to be susceptible to contracting and spreading the virus back to humans.

ABOVE: © ISTOCK.COM, CONTOURPM

ace2

Decoy Cells Trick SARS-CoV-2, Reduce Cytokines In Vitro
Max Kozlov | Oct 14, 2020
Genetically engineered cells that overproduce ACE2, the receptor the novel coronavirus uses to enter cells, neutralize infection in vitro and mop up inflammatory cytokines in mice.
Stomach Acid & Heartburn Drugs Linked with COVID-19 Outcomes
Ashley Yeager | Oct 7, 2020
While sick with COVID-19, President Trump is taking an antacid. Doctors have been exploring whether these medicines can treat SARS-CoV-2 infections, and the results are mixed.
Accelerating Discovery in the Age of a Pandemic
The Scientist Creative Services Team | Jan 22, 2021
An expert panel will present how synthetic biology accelerates the development of diagnostics, therapeutics, and the medicinal pipeline.
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Modeling Study Flags Species Susceptible to SARS-CoV-2
Anthony King | Aug 26, 2020
Some critically endangered animals are on the list.
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Is a Bradykinin Storm Brewing in COVID-19?
Alakananda Dasgupta | Aug 26, 2020
Excess of the inflammatory molecule bradykinin may explain the fluid build-up in the lungs of patients with coronavirus infections. Clinical trials of inhibitors are putting this hypothesis to the test.
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Infographic: SARS-CoV-2 Interferes with Bradykinin Regulation
Alakananda Dasgupta | Aug 26, 2020
The leaky blood vessels and lung fluid build-up in some COVID-19 patients might be explained by the virus’s corruption of an inflammation safeguard.
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SARS-CoV-2 Can Infect Human Brain Organoids
Katarina Zimmer | Jul 9, 2020
The results are a proof-of-concept that the novel coronavirus can replicate in neurons, but it’s too soon to say whether this occurs in people with COVID-19.
SARS-CoV-2 Spike Protein Shares Sequence with a Human Protein
Abby Olena | Jun 1, 2020
Eight amino acids are identical to part of the human epithelial sodium channel, leading researchers to suspect the virus might interfere with the channel’s function.
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Receptors for SARS-CoV-2 Present in Wide Variety of Human Cells
Chris Baraniuk | Apr 29, 2020
Analyses from single-cell sequencing datasets support the idea that COVID-19 is not just a respiratory disease but an illness that can affect multiple organs.
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Scientists Scan for Weaknesses in the SARS-CoV-2 Spike Protein
Chris Baraniuk | Apr 9, 2020
The virus’s tool for prying open host cells is coated in a protective armor of sugar—but gaps may offer vulnerability to disruption by antibodies.
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Possible Biological Explanations for Kids’ Escape from COVID-19
Anthony King | Mar 16, 2020
Infected children may harbor SARS-CoV-2 while showing less-severe symptoms than adults. Their young immune systems, ACE2 receptor levels, and even exposure to other coronaviruses might play a role in their resilience.