The sei ion channel in fruit flies keeps their neuronal excitability in check.

Johns Hopkins’s Ted Dawson discusses his lab’s demonstration that misfolded α-synuclein can move from the stomach to the brain and cause physical and cognitive symptoms.

The move reflects scientists using more cell lines and organoids in genetic research, although some experts disagree with the decision to scale back the use of animal models.

Machine learning could be the key to reducing the use of animals in experiments.

Scientists say that increasingly rigorous licensing procedures have complicated research efforts—and in some cases, stopped experiments completely.

A report finds a decline in the number of experiments involving animals in 2017, noting a particular decrease in procedures on dogs and primates.

Including as few as two labs in a study improved the odds of getting the true effect size by as much as 23 percentage points, according to a replication model.

After years of obscurity, strains of mice with mutations in particular genes are thrust to the fore of autism research.

When transplanted into mice, tumor genomes evolve differently than they do in patients, study finds.