Mice rendered infertile through ovary cell–targeting mutations gave birth to seemingly normal offspring through natural mating after a virus-based gene therapy was injected into their ovaries.

Researchers find a way to wipe out the brain’s immune cell corps and send in new and improved versions.

The University of Southern California bioengineer studies how lizards regrow their tails, with the goal of one day inducing regeneration in humans.

Tracking human cancers in mice shows some unexpected cell changes that could undermine translational research.  

The color morph’s bright yellow hue and its propensity for skin tumors both likely stem from a gene implicated in a dangerous form of human skin cancer, suggesting the animals could make an ideal model for studying the disease.

Researchers turn to familiar model animals, along with some fresh strategies, to develop countermeasures against SARS-CoV-2 and investigate the biology of infection.

The University of Alabama at Birmingham neuroscientist aims to determine which cells are most important in prompting the disease’s initiation and progression.

When mice that had suffered a stroke were given blood from a healthy donor, they experienced less tissue and neurological damage.

The Johns Hopkins University researcher bucked the prevailing idea that the body would not launch an immune response against its own tissues, and in doing so established an entirely new scientific discipline.

A newly engineered synthetic blood vessel offers a novel platform for developing drugs that treat high blood pressure.

The host transcriptional signature elicited by the coronavirus appears to be less robust and lacks the induction of key antiviral genes.

Many researchers have stopped breeding mice, reduced the size of colonies, and established contingency plans in case animal care staff get sick.

Rhesus macaques can be infected with SARS-CoV-2, leading primate center scientists to try to prevent outbreaks in their colonies, especially as experiments on coronavirus start.