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Image of the Day
Want to Boost Reproducibility? Get Another Lab Involved
Jim Daley | Feb 22, 2018
Including as few as two labs in a study improved the odds of getting the true effect size by as much as 23 percentage points, according to a replication model.
“Retired” Mice Find New Life as Top Models for Autism
Jessica Wright | Jan 29, 2018
After years of obscurity, strains of mice with mutations in particular genes are thrust to the fore of autism research.
Study Raises Questions About Patient-Derived Xenografts
Ashley P. Taylor | Oct 10, 2017
When transplanted into mice, tumor genomes evolve differently than they do in patients, study finds.
Image of the Day: Fish Avatars for Cancer
Staff | Sep 11, 2017
Zebrafish larvae transplanted with patients’ tumors respond as their human donors do to chemotherapy.
Zebrafish Embryos Survive Deep Freeze and Quick Thaw
Ashley Yeager | Jul 28, 2017
In a first, scientists reanimate the fish using embedded gold nanoparticles that heat up cells by absorbing laser light.
First Genetic Screen of Pigs Using ENU
Ashley Yeager | Jul 14, 2017
Using the mutagenic chemical N-ethyl-N-nitrosourea, researchers confirm the role of a gene in a piglet deformity and identify potential models for human diseases.
Artificial Womb Supports Premature Fetal Lamb Development
Tracy Vence | Apr 25, 2017
The lungs of extremely premature lambs supported in a closed, sterile environment that enables fluid-based gas exchange grow and develop normally, researchers report.
Scientists Successfully Transplant Human Leukemia Cells into Mice
Diana Kwon | Apr 1, 2017
While studying the progression of healthy cells into cancerous ones, researchers discover a way to engraft human blood cells into animals.
Opinion: Canine Models for Alzheimer’s
Edward G. Barrett | Mar 1, 2017
For research on drugs to treat neurodegenerative diseases, dogs offer a better predictor of clinical outcomes.
Opinion: Reuse and Reduce
Valerie Speirs | Jan 16, 2017
Sharing leftover samples from preclinical experiments is one way biomedical researchers can make the most of animal models.