Lung Cancer Cells Switch Oncogenic Drivers
Lung Cancer Cells Switch Oncogenic Drivers
Mouse models mimicking the transition from a common form of lung cancer to a more aggressive one may help scientists develop future strategies to prevent this transformation.
Mouse models mimicking the transition from a common form of lung cancer to a more aggressive one may help scientists develop future strategies to prevent this transformation.
cancer stem cells
Understanding Cancer Evolution Through the Lens of Single Cell Genomics
The Scientist | Oct 14, 2021 | 1 min read
Nicholas Navin and Lars Velten discuss sampling, sequencing, and tracing single cells to study how cancer cells adapt to various environments.
Bisrat Debeb Models How Cancer Spreads to the Brain
Catherine Offord | Apr 1, 2021 | 3 min read
From his student days in veterinary medicine in Ethiopia to running a lab on metastasis at MD Anderson Cancer Center, Debeb has a passion for understanding how living things work.
Leukemia Relapses May Arise From Specialized Cells
Sukanya Charuchandra | Dec 1, 2018 | 2 min read
Targeting the transient group of cells could prevent recurrence of the disease.
Antibody Therapy Targets Cancer Stem Cells: Study
Joshua A. Krisch | Mar 15, 2017 | 4 min read
CT16 appears to eliminate cancer stem cells more effectively than radiation therapy in vitro and has shown promise in mice.
More Than Skin Deep
Anna Azvolinsky | May 1, 2016 | 9 min read
Elaine Fuchs has worked on adult stem cells since before they were so named, figuring out how multipotent epidermal cells renew or turn into skin or hair follicles.
Fuchs on the Future
The Scientist | Apr 30, 2016 | 1 min read
Rockefeller University researcher Elaine Fuchs on being a woman in science and her contributions to the burgeoning field of reverse genetics
In Custody
Wudan Yan | Apr 1, 2015 | 8 min read
Expert tips for isolating and culturing cancer stem cells
Stem Cell Alter Egos
Abby Olena, PhD | Apr 1, 2014 | 2 min read
Researchers show that cancer stem cells can exist in two distinct and interconvertible states.
Master of Fate
Megan Scudellari | Jul 1, 2013 | 9 min read
While tracing the tricky and sometimes surprising paths of multipotent cells in the skin, mammary gland, and heart, Cédric Blanpain has repeatedly turned the stem cell field on its head.
Waking Cancer Cells
Beth Marie Mole | Dec 1, 2012 | 2 min read
A protein called Coco rouses dormant breast cancer cells in the lung.
Stem Cells Not Needed for Cancer
Ruth Williams | Oct 18, 2012 | 3 min read
Fully developed neurons can revert to stem cell-like states and give rise to brain tumors.
Cancer Stem Cells Really Do Exist?
Sabrina Richards | Aug 1, 2012 | 4 min read
Researchers track tumors as they develop, providing more support for the idea that cells with stem-cell-like properties underlie cancer growth and recurrence.
Contributors
The Scientist Staff | Apr 1, 2012 | 3 min read
Meet some of the people featured in the April 2012 issue of The Scientist.
Agents Provocateurs
Mary Beth Aberlin | Apr 1, 2012 | 3 min read
Asking pointed questions is a key part of the scientific process.
The Two Faces of Metastasis
Suling Liu, Hasan Korkaya, and Max S. Wicha | Apr 1, 2012 | 1 min read
During development, the cells of an embryo change their pattern of gene expression, which allows them to detach from their original location and migrate to another part of the embryo, where the pattern changes again to allow formation of a new organ.
Are Cancer Stem Cells Ready for Prime Time?
Suling Liu, Hasan Korkaya, and Max S. Wicha | Apr 1, 2012 | 10+ min read
A flood of new discoveries has refined our definition of cancer stem cells. Now it’s up to human clinical trials to test if they can make a difference in patients.