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hCINAP Protein Key to Cellular Senescence: Study
hCINAP Protein Key to Cellular Senescence: Study
The authors claim that by preventing the formation of senescent cells, the protein could delay aging, but experts are skeptical.
The authors claim that by preventing the formation of senescent cells, the protein could delay aging, but experts are skeptical.
cell senescence
Cellular Senescence: Why Do Cells Stop Dividing?
Elina Kadriu | Feb 28, 2023 | 4 min read
Senescent cells undergo major morphological and metabolic changes when at the end of their lifespan.
The Scientist Speaks - Exploring the Secrets to Longevity and Cancer Resistance in Mole-Rats
The Scientist | Oct 24, 2022 | 1 min read
Vera Gorbunova discusses what naked and blind mole-rat cells reveal about aging and cancer resistance mechanisms.
T Cells Ward Off Aging with Help from Their Friends
Natalia Mesa, PhD | Sep 16, 2022 | 5 min read
Immune cells deliver packages of telomeres to T cells, helping them retain their virus-fighting function over time, research suggests.
Can Destroying Senescent Cells Treat Age-Related Disease?
Katarina Zimmer | Mar 1, 2020 | 10+ min read
A handful of clinical trials are underway to find out whether drugs that target senescent cells can slow the ravages of old age.
Infographic: How Does Cell Senescence Drive Aging and Disease?
Katarina Zimmer | Mar 1, 2020 | 4 min read
The accumulation of zombie-like cells seems to accelerate aging and promote aging-related disease. Researchers are trying to figure out how.
Cellular Senescence in Astrocytes May Play Central Role in Parkinson’s Disease
Katarina Zimmer | Jan 24, 2018 | 4 min read
The elimination of these glia in the mouse brain ameliorated the development of Parkinsonian neuropathologies induced by the pesticide toxin paraquat.
Slowing Aging
Catherine Offord | Feb 4, 2016 | 2 min read
The removal of senescent cells in mice leads to an increased lifespan and later onset of age-linked diseases, scientists show.
Setbacks and Great Leaps
Sue Armstrong | Apr 1, 2015 | 3 min read
The tale of p53, a widely studied tumor suppressor gene, illustrates the inventiveness of researchers who turn mishaps into discoveries.
Book Excerpt from p53
Sue Armstrong | Mar 31, 2015 | 4 min read
In Chapter 12, "Of Mice and Men," author Sue Armstrong recounts the point at which researchers moved from working with p53 in tissue culture to studying the gene in animal models.
Of Cells and Limits
Anna Azvolinsky | Mar 1, 2015 | 9 min read
Leonard Hayflick has been unafraid to speak his mind, whether it is to upend a well-entrenched dogma or to challenge the federal government. At 86, he’s nowhere near retirement.