Can Destroying Senescent Cells Treat Age-Related Disease?
Can Destroying Senescent Cells Treat Age-Related Disease?
A handful of clinical trials are underway to find out whether drugs that target senescent cells can slow the ravages of old age.
Can Destroying Senescent Cells Treat Age-Related Disease?
Can Destroying Senescent Cells Treat Age-Related Disease?

A handful of clinical trials are underway to find out whether drugs that target senescent cells can slow the ravages of old age.

A handful of clinical trials are underway to find out whether drugs that target senescent cells can slow the ravages of old age.

cell senescence
Infographic: How Does Cell Senescence Drive Aging and Disease?
Infographic: How Does Cell Senescence Drive Aging and Disease?
Katarina Zimmer | Mar 1, 2020
The accumulation of zombie-like cells seems to accelerate aging and promote aging-related disease. Researchers are trying to figure out how.
Cellular Senescence in Astrocytes May Play Central Role in Parkinson’s Disease
Cellular Senescence in Astrocytes May Play Central Role in Parkinson’s Disease
Katarina Zimmer | Jan 24, 2018
The elimination of these glia in the mouse brain ameliorated the development of Parkinsonian neuropathologies induced by the pesticide toxin paraquat.  
Slowing Aging
Slowing Aging
Catherine Offord | Feb 4, 2016
The removal of senescent cells in mice leads to an increased lifespan and later onset of age-linked diseases, scientists show.
Book Excerpt from <em>p53</em>
Book Excerpt from p53
Sue Armstrong | Mar 31, 2015
In Chapter 12, "Of Mice and Men," author Sue Armstrong recounts the point at which researchers moved from working with p53 in tissue culture to studying the gene in animal models.
Setbacks and Great Leaps
Setbacks and Great Leaps
Sue Armstrong | Mar 31, 2015
The tale of p53, a widely studied tumor suppressor gene, illustrates the inventiveness of researchers who turn mishaps into discoveries.
Of Cells and Limits
Of Cells and Limits
Anna Azvolinsky | Feb 28, 2015
Leonard Hayflick has been unafraid to speak his mind, whether it is to upend a well-entrenched dogma or to challenge the federal government. At 86, he’s nowhere near retirement.