cell senescence
Cellular Senescence in Astrocytes May Play Central Role in Parkinson’s Disease
Cellular Senescence in Astrocytes May Play Central Role in Parkinson’s Disease
Katarina Zimmer | Jan 24, 2018
The elimination of these glia in the mouse brain ameliorated the development of Parkinsonian neuropathologies induced by the pesticide toxin paraquat.  
Slowing Aging
Slowing Aging
Catherine Offord | Feb 5, 2016
The removal of senescent cells in mice leads to an increased lifespan and later onset of age-linked diseases, scientists show.
Book Excerpt from <em>p53</em>
Book Excerpt from p53
Sue Armstrong | Apr 1, 2015
In Chapter 12, "Of Mice and Men," author Sue Armstrong recounts the point at which researchers moved from working with p53 in tissue culture to studying the gene in animal models.
Setbacks and Great Leaps
Setbacks and Great Leaps
Sue Armstrong | Apr 1, 2015
The tale of p53, a widely studied tumor suppressor gene, illustrates the inventiveness of researchers who turn mishaps into discoveries.
Of Cells and Limits
Of Cells and Limits
Anna Azvolinsky | Mar 1, 2015
Leonard Hayflick has been unafraid to speak his mind, whether it is to upend a well-entrenched dogma or to challenge the federal government. At 86, he’s nowhere near retirement.