Despite recent advances in the study of eukaryogenesis, much remains unresolved about the origin and evolution of the most complex domain of life.

A lot happened in the hundreds of millions years separating the first and last eukaryotic common ancestors, but when and how most features arose remains a mystery.

With ever-advancing genetic technologies, researchers continue to document the genetic code of the human species.

Thirty years out from the start of the Human Genome Project, researchers have finally finished sequencing the full 3 billion bases of a person’s genetic code. But even a complete reference genome has its shortcomings.

The findings will likely help elucidate the effects of chromosome fusions, which can cause disease but have also contributed to evolution.

A new link between inflammation and rampant chromosomal abnormalities reveals novel strategies to treat diverse malignancies.

When micronuclei rupture, chromosomes break, recombine, and form circles, causing inflammation and promoting carcinogenic growth.

The Scientist interviews evolutionary biologist Carles Vilà about how a large genomic inversion detected in common quail affects the birds’ physical characteristics and migratory behaviors.

Researchers discover surprisingly high levels of genetic diversity among the colorful male morphs of a freshwater fish.

A “larger than life personality,” Amon devoted her career to studying the cell cycle and aneuploidy. Her research has shaped the field of cancer biology.

The University of Alabama at Birmingham neuroscientist aims to determine which cells are most important in prompting the disease’s initiation and progression.

Three studies identify unintended consequences of gene editing in human embryos, including large deletions and reshuffling of DNA.

A phthalate commonly found in shampoos, cosmetics, and cleaning products disrupts reproduction in worms.

The DNA-protein complex has branches that fold back on themselves.

Integrating a specialized histone into large segments of transgenic DNA enables centromere formation.

Recruiting an epigenetic instigator of centromere formation into large segments of cloned DNA facilitates their transformation into artificial chromosomes.