Conceptual image showing fragmented X chromosomes
How Chaos in Chromosomes Helps Drive Cancer Spread
A new link between inflammation and rampant chromosomal abnormalities reveals novel strategies to treat diverse malignancies.
ABOVE: MODIFIED FROM © ISTOCK.COM, DR_MICROBE
How Chaos in Chromosomes Helps Drive Cancer Spread
How Chaos in Chromosomes Helps Drive Cancer Spread

A new link between inflammation and rampant chromosomal abnormalities reveals novel strategies to treat diverse malignancies.

A new link between inflammation and rampant chromosomal abnormalities reveals novel strategies to treat diverse malignancies.

ABOVE: MODIFIED FROM © ISTOCK.COM, DR_MICROBE

chromosome

Infographic showing how bursting micronuclei promote cancer
Infographic: Chromosome Errors Cause Micronuclei and Drive Cancer
Samuel F. Bakhoum | Mar 1, 2022
When micronuclei rupture, chromosomes break, recombine, and form circles, causing inflammation and promoting carcinogenic growth.
two quails
Chromosomal Rearrangement Linked to Less Mobile Quail
Chloe Tenn | Dec 7, 2021
The Scientist interviews evolutionary biologist Carles Vilà about how a large genomic inversion detected in common quail affects the birds’ physical characteristics and migratory behaviors.
Abstract Genetics Disease stock photo
Bridging Disciplines to Study CRISPR-Induced Chromosome Destabilization
Aparna Nathan | Apr 8, 2022
A collaboration between friends led to a cautionary finding about CRISPR’s effect on cells.
Five morphs of Poecilia parae—from top: melanzona yellow, melanzona blue, melanzona red, parae, immaculata—and a female (bottom) of the same species
Fish Species’ Y Chromosomes Diverged Even Without Recombination
Catherine Offord | Sep 1, 2021
Researchers discover surprisingly high levels of genetic diversity among the colorful male morphs of a freshwater fish.
Cell Biologist Angelika Amon Dies at 53
Max Kozlov | Nov 4, 2020
A “larger than life personality,” Amon devoted her career to studying the cell cycle and aneuploidy. Her research has shaped the field of cancer biology.
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Investigating Genetic and Epigenetic Landscapes with Long-Read Sequencing
The Scientist Creative Services Team in collaboration with Oxford Nanopore | Aug 13, 2021
Matthew Naish will discuss what he learned about Arabidopsis thaliana centromeres from long-read sequencing experiments.
Michelle Gray Tracks Huntington’s in Different Brain Cells
Amanda Heidt | Oct 1, 2020
The University of Alabama at Birmingham neuroscientist aims to determine which cells are most important in prompting the disease’s initiation and progression.
gene, CRISPR, CRISPR-Cas9, gene editing, human embryo, chromosome, mutation, deletion
CRISPR Gene Editing Prompts Chaos in DNA of Human Embryos
Amanda Heidt | Jun 26, 2020
Three studies identify unintended consequences of gene editing in human embryos, including large deletions and reshuffling of DNA.
Scaling BAC on Time and Sample
The Scientist Creative Services Team in collaboration with Agilent Technologies | Apr 9, 2021
A new and simplified quality control method confirms the cloning of both small and large inserts in bacterial artificial chromosomes (BACs) with significantly less time and sample.
Image of the Day: Impaired Meiosis
Amy Schleunes | Feb 7, 2020
A phthalate commonly found in shampoos, cosmetics, and cleaning products disrupts reproduction in worms.
Image of the Day: Chromatin Forest
Emily Makowski | Jan 14, 2020
The DNA-protein complex has branches that fold back on themselves.
Infographic: Building an Artificial Chromosome
Ruth Williams | Nov 1, 2019
Integrating a specialized histone into large segments of transgenic DNA enables centromere formation.
Streamlined Artificial Chromosome Creation
Ruth Williams | Nov 1, 2019
Recruiting an epigenetic instigator of centromere formation into large segments of cloned DNA facilitates their transformation into artificial chromosomes.
Unbalanced Chromosomal Inheritance More Common than Thought
Jef Akst | Oct 11, 2019
A genomic analysis from 23andMe suggests that people inherit two copies of a chromosome from only one parent nearly twice as often as researchers had realized.
Liane Russell geneticist
Geneticist Liane Russell Dies
Nicoletta Lanese | Jul 29, 2019
She conducted innovative research in mutagenesis and teratogenesis related to radiation and chemical exposures, identifying risks to fetuses.
nettie stevens x and y chromosome name origin the scientist
How Chromosomes X and Y Got Their Names, 1891
Joseph Keierleber | Mar 1, 2019
A quirk of nomenclature originates in the study of insect cells.
Infographic: Effects of Satellite DNA–Binding Proteins
Sukanya Charuchandra | Oct 1, 2018
The linkers gather chromosomes together into chromocenters.
Chromosome Clusters Help Keep the Genome Together
Sukanya Charuchandra | Oct 1, 2018
Without certain DNA-binding proteins, chromosomes can escape the cell nucleus.
Researchers Fuse Chromosomes to Create New Yeast Strains
Diana Kwon | Aug 1, 2018
Saccharomyces cerevisiae showed only minor alterations in growth and gene expression when its 16 chromosomes were combined.