directed evolution
Optimize Protein Characteristics While Retaining Their Original Function
Optimizing Protein Function with Combinatorial Variant Libraries
Twist Bioscience | Sep 29, 2021
Researchers perform directed evolution using a variant library engineered to avoid complications associated with traditional libraries.
Directed Evolution, Phage Display Nab Chemistry Nobel
Catherine Offord and Kerry Grens | Oct 3, 2018
The 2018 award goes to Frances Arnold, Gregory Winter, and George Smith.
Engineered Bacteria Build Carbon-Silicon Bonds
Joshua A. Krisch | Nov 28, 2016
Researchers tweak bacterial proteins, turning them into powerful enzymes capable of producing silicon-carbon compounds naturally and more efficiently than manmade catalysts.
Reverse Transcriptase with Proofreading Capabilities Created
Alison F. Takemura | Jun 27, 2016
Using directed evolution, researchers selected a DNA polymerase to copy RNA into DNA.
Chemical Engineer Wins Millennium Technology Prize
Tanya Lewis | May 25, 2016
Caltech’s Frances Arnold is honored for her work on directed evolution.
Genes Get in Your Eye
Ruth Williams | Jun 12, 2013
Directed evolution of a gene therapy virus vector improves its penetration into the retina.
Flies Evolve to Count
Hayley Dunning | Jul 12, 2012
Researchers breed fruit flies that, after 40 generations of conditioning, have acquired the ability to react to numbers.
The Immune System as a Tool for Directed Evolution
Aileen Constans | Jan 30, 2005
A team of researchers at the University of California, San Diego, has harnessed the body's ability to tweak antibody genes to drive protein evolution in the lab.