Researchers Engineer Epigenome Editors to Study How Gene Expression Affects Disease
Researchers Engineer Epigenome Editors to Study How Gene Expression Affects Disease
Using CRISPR and other tools, scientists are modifying DNA methylation, histone marks, and other modifiers of gene expression to understand how they affect health and disease.
Researchers Engineer Epigenome Editors to Study How Gene Expression Affects Disease
Researchers Engineer Epigenome Editors to Study How Gene Expression Affects Disease

Using CRISPR and other tools, scientists are modifying DNA methylation, histone marks, and other modifiers of gene expression to understand how they affect health and disease.

Using CRISPR and other tools, scientists are modifying DNA methylation, histone marks, and other modifiers of gene expression to understand how they affect health and disease.

epigenome
Q&A: A 10,000-Genome Milestone for Shared Pediatric Cancer Data  
Q&A: A 10,000-Genome Milestone for Shared Pediatric Cancer Data  
Carolyn Wilke | Apr 1, 2019
Computational biologist Jinghui Zhang of St. Jude realized scientists could work more efficiently with tools and genomic data shared on the cloud.
Analysis of 2,000 Brains Provides Clues to Schizophrenia, Autism
Analysis of 2,000 Brains Provides Clues to Schizophrenia, Autism
Catherine Offord | Dec 14, 2018
The PsychENCODE project delves into the DNA, RNA, and protein changes related to brain development and neuropsychiatric disorders, but researchers caution it’s just a first step toward treatment.
Study Finds Epigenetic Differences Between Hatchery-Raised and Wild-Born Salmon
Study Finds Epigenetic Differences Between Hatchery-Raised and Wild-Born Salmon
Shawna Williams | Mar 1, 2018
The variation may help explain why stocked salmon don’t fare as well in the ocean.
Exploring the Epigenetics of Ethnicity
Exploring the Epigenetics of Ethnicity
Anna Azvolinsky | Jan 10, 2017
Researchers attempt to estimate how much of the human genome’s methylation patterns can be attributed to genetic ancestry.
Opinion: Engineering the Epigenome
Opinion: Engineering the Epigenome
Anna Köferle, Stefan H. Stricker, Stephan Beck | Aug 26, 2015
The use of targetable chromatin modifiers has ushered in a new era of functional epigenomics.
New Epigenetic Mark Found on Metazoan DNA
New Epigenetic Mark Found on Metazoan DNA
Jenny Rood | Apr 30, 2015
Three studies identify roles for N6-methyladenosine in algae, worms, and flies.
CRISPR–Enabled Epigenome Editing
CRISPR–Enabled Epigenome Editing
Kerry Grens | Apr 6, 2015
Researchers apply the genome-editing technology to alter histones at distant gene enhancers, controlling gene expression.
Exploring the Epigenome
Exploring the Epigenome
Jenny Rood | Feb 18, 2015
A National Institutes of Health-funded consortium publishes 111 reference maps of DNA and histone marks.
Methylation Tied to Alzheimer’s
Methylation Tied to Alzheimer’s
Kerry Grens | Aug 20, 2014
People with the neurodegenerative disease are more likely to have certain epigenetic patterns than those without.