Alcohol bottles at a bar
Epigenome Editing Decreases Alcohol Seeking and Anxiety in Rats
A CRISPR-based system that reverses epigenetic changes caused by adolescent binge drinking reduces adult addiction-like behaviors in rats, a study finds, suggesting that an epigenomic approach could someday help treat people with alcohol use disorder.
ABOVE: © iStock.com, Semen Salivanchuk
Epigenome Editing Decreases Alcohol Seeking and Anxiety in Rats
Epigenome Editing Decreases Alcohol Seeking and Anxiety in Rats

A CRISPR-based system that reverses epigenetic changes caused by adolescent binge drinking reduces adult addiction-like behaviors in rats, a study finds, suggesting that an epigenomic approach could someday help treat people with alcohol use disorder.

A CRISPR-based system that reverses epigenetic changes caused by adolescent binge drinking reduces adult addiction-like behaviors in rats, a study finds, suggesting that an epigenomic approach could someday help treat people with alcohol use disorder.

ABOVE: © iStock.com, Semen Salivanchuk

epigenomics

5 images related to stories highlighted in the article, including DNA strand, insect, and dog
Our Favorite Genetics Stories of 2021
Christie Wilcox | Dec 23, 2021
Studies The Scientist covered this year illustrate the expanding importance of genetic and genomic research in all aspects of life science, from ecology to medicine.
early-life stress, histone, chromatin, epigenetics, epigenetic modification, methylation, DNA, protein, stress, adversity, mice, genetics, genomics
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
Asher Jones | Mar 18, 2021
In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.
Sample Preparation with Single Cell Multiomics: Simultaneous Epigenomic and Transcriptomic Profiling from the Same Cell
The Scientist Creative Services Team | Sep 30, 2020
In this webinar brought to you by 10x Genomics, experts will discuss how to successfully prepare nuclei suspensions for Single Cell Multiome ATAC + Gene Expression experiments.
Computational Biologist James Taylor Dies
Lisa Winter | Apr 7, 2020
The Johns Hopkins University professor was a co-developer of the Galaxy platform, an open-source bioinformatics tool used in labs around the world.
Opinion: Engineering the Epigenome
Anna Köferle, Stefan H. Stricker, Stephan Beck | Aug 26, 2015
The use of targetable chromatin modifiers has ushered in a new era of functional epigenomics.
Capsule Reviews
Bob Grant | Jul 1, 2015
Stoned, Anxious, The Deeper Genome, and Testosterone
Estimating Epigenetic Mutation Rates
Jenny Rood | May 11, 2015
Generation-spanning maps of Arabidopsis thaliana DNA methylation allow researchers to compute how quickly epigenetic marks appear and disappear in the plant’s genome.
Exploring the Epigenome
Jenny Rood | Feb 18, 2015
A National Institutes of Health-funded consortium publishes 111 reference maps of DNA and histone marks.
A Guide to the Epigenome
Jeffrey M. Perkel | Nov 1, 2012
Making sense of the data deluge