With multiple applications in biomedicine, the antibodies can now be made quickly, cheaply, and without the need for an alpaca or one of its relatives.

To tease apart brain regions involved in forming versus remembering memories, scientists engineered mice whose brain cells could be manipulated and tagged.

To track distinct populations of developing cardiovascular cells, scientists used pulses of electricity to introduce fluorescently labeled DNA into chick embryos.

Roger Tsien R.I.P., predatory publishing, and diversity in science

One of the pioneers in developing fluorescent proteins for biological studies was 64 years old.

“Ultimate DISCO” uses a solvent that shrinks whole animals and preserves fluorescence for months.

Engineered proteins can tether multiple fluorescent molecules to give a brighter signal—and that’s not all.

Scientists engineer fluorescing nematodes to project the worms’ expected lifespans through flashes of light at just three days old.

The Japanese freshwater eel is the first vertebrate found to produce a fluorescent protein, which may prove useful in the clinic.