A new tool called PRISM draws on virus-host interactions and a DNA repair pathway to help researchers visualize how cellular stress may contribute to neurodegenerative disease.

In yellow-green and purple versions of the reef-building Acropora tenuis, the genes that code for particular fluorescent and other colorful proteins become more active in the summer, protecting symbiotic algae from thermal stress and resisting bleaching.

With multiple applications in biomedicine, the antibodies can now be made quickly, cheaply, and without the need for an alpaca or one of its relatives.

To tease apart brain regions involved in forming versus remembering memories, scientists engineered mice whose brain cells could be manipulated and tagged.

To track distinct populations of developing cardiovascular cells, scientists used pulses of electricity to introduce fluorescently labeled DNA into chick embryos.

Roger Tsien R.I.P., predatory publishing, and diversity in science

One of the pioneers in developing fluorescent proteins for biological studies was 64 years old.

“Ultimate DISCO” uses a solvent that shrinks whole animals and preserves fluorescence for months.

Engineered proteins can tether multiple fluorescent molecules to give a brighter signal—and that’s not all.

Scientists engineer fluorescing nematodes to project the worms’ expected lifespans through flashes of light at just three days old.

The Japanese freshwater eel is the first vertebrate found to produce a fluorescent protein, which may prove useful in the clinic.

The first researcher to clone the gene for green fluorescent protein, but who was passed over for the 2008 Nobel Prize in Chemistry, is back in academic science.

Biologist David Gruber studies radiant creatures and their fluorescent proteins.

How to track RNA in living cells

Researchers design patterns of fluorescent protein expression to deliver secret messages.