Pink rat pups piled on top of each other.
Rat Sperm Generated from Stem Cells
Researchers report they were able to make functional sperm in a dish, a feat previously only possible for mice.
ABOVE: TOSHIHIRO KOBAYASHI, Ph.D., IMSUT/NIPS
Rat Sperm Generated from Stem Cells
Rat Sperm Generated from Stem Cells

Researchers report they were able to make functional sperm in a dish, a feat previously only possible for mice.

Researchers report they were able to make functional sperm in a dish, a feat previously only possible for mice.

ABOVE: TOSHIHIRO KOBAYASHI, Ph.D., IMSUT/NIPS

germ cells

Eight Proteins Turn Mouse Stem Cells into Egglike Cells
Ashley Yeager | Dec 16, 2020
The identification of the transcription factors that elicit oocyte growth will aid reproductive biology research and might help women with fertility issues, scientists say.  
Single-Cell Analysis of Ovarian Cortex Fails to Find Stem Cells
Amy Schleunes | Mar 6, 2020
The controversial oogonial stem cells eluded a team of Swedish researchers who mapped high-quality tissue samples of the human ovary, prompting more questions about the cells’ existence.  
primordial germ cells
Stray Germ Cells May Seed Female-Biased Cancerous Cysts
Ashley Yeager | Apr 1, 2019
Similarities in gene expression hint at the origin of a certain type of pancreatic tumor that predominantly afflicts women.
Researchers Cryopreserve Coral Sperm
Catherine Offord | Feb 1, 2018
A project aims to preserve samples of the climate change–vulnerable animals for future restoration.
Sea Anemones Illuminate the Evolution of Embryo Development
Abby Olena | Sep 11, 2017
A study of a simple marine animal suggests that the common ancestor of cnidarians and bilaterians may have had three germ layers instead of two.
From Stem Cell to Oocyte In a Dish
Anna Azvolinsky | Oct 17, 2016
For the first time, scientists generate functional mouse eggs from stem cells in culture.
Sperm From Ovaries
Anna Azvolinsky | Jun 11, 2015
With the deletion of a single gene, female Japanese rice fish can produce sperm. 
Erasing Mitochondrial Mutations
Jenny Rood | Apr 23, 2015
Researchers develop a method to selectively remove mutated mitochondrial DNA from the murine germline and single-celled mouse embryos.
Mouse Eggs Made with Stem Cells
Dan Cossins | Oct 4, 2012
Researchers claim to have successfully transformed stem cells into viable mouse oocytes that produced healthy, fertile pups.
Lab-Grown Sperm
Cristina Luiggi | Aug 4, 2011
Healthy mice are born from germ cell precursors grown in vitro.