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| 3 min read
From microglia reprogramming to immune cell-based diagnostics, 2025 was a big year for breakthroughs in cell biology.

immune profiling

Single cells rendered in 3D

Capturing Complexity Cell by Cell

Find out how to overcome CAR T cell therapy’s biggest challenges 

High-Resolution CAR T Cell Analysis

Small Changes, Big Consequences

Small Changes, Big Consequences

Explore single cell and spatial methods for studying cancer biology

Analyzing Multiple Dimensions of Cancer Biology

Find the right storage conditions for blood samples destined for single cell sequencing experiments

How Do Storage Conditions Alter Single Cell Gene Expression Data Quality?

Discover How to Enhance Cell and Gene Therapy Efficacy and Safety

Technologies to Transform Cell and Gene Therapy Development

Monitor and analyze cancer cell therapies

Monitoring Cancer Immune Cell Therapies

Technique Talk: Single Cell Sequencing Sample Preparation for Oncology Research

Improving COVID-19 Treatment & Vaccine Development by Modulating the Immune Response: Applying Single-Cell Proteomics 

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Sex-Specific Dioxin Toxicity in a Humanized AHR Model

Sex-Specific Dioxin Toxicity in a Humanized AHR Model

Miltenyi
Image of Nobel Prize medal on a table.

Who Will Win the 2026 Nobel Prize? Scientists Make Their Predictions

Black and gold sketch of Henri Kagan and Kenso Soai, who won this year’s Nobel Prize in Chemistry.

Chemistry Nobel Prize for Asymmetric Organic Synthesis

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

Multimedia

Evaluating Blood Biomarkers for Alzheimer’s Disease Staging

Evaluating Blood Biomarkers for Alzheimer’s Disease Staging

​Beckman Coulter
Three-dimensional illustration of a curved, single-stranded RNA molecule against a blue background

Gene Editing Precision Depends on Guide RNA Quality

TriLink BioTechnologies
The Scientist October Digest cover
October 2026

Antarctica’s Blood Falls Teems With Mysterious Microbial Life

Miles away from the closest ocean, marine microbes thrive in the red ice and mud around Blood Falls, offering clues to microbial adaptation and past climate events.

View this Issue
Evaluating Blood Biomarkers for Alzheimer’s Disease Staging

Evaluating Blood Biomarkers for Alzheimer’s Disease Staging

​Beckman Coulter
Find better biologics faster with Stunner and the AI Developability Workcell

Find better biologics faster with Stunner and the AI Developability Workcell

Unchained Labs
An image of microcentrifuge tubes arranged within colorful laboratory racks.

Choose clarity. Choose speed. Choose MyMass™

Refeyn
Characterizing LNP Heterogeneity With Super-Resolution Imaging

Characterizing LNP Heterogeneity With Super-Resolution Imaging

Oni

Products

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Stellaromics Expands Pyxa Adoption as Instruments are Installed at Leading Research Institutions Across the U.S. and EuropeStellaromics, Inc., the leader in 3D

A monoclonal antibody surrounded by immune cells and red blood cells

CellRaft AIR: Find the Right Antibody-Producing Cells Faster

Cell Microsystems
Maxwell® Rapid ccfDNA Kit

Maxwell® Rapid ccfDNA Kit: Automated Purification of ccfDNA in Under 30 Minutes

Promega
Leica Biosystems, Tempus, and Paige logos side by side, marking the addition of Paige digital pathology AI tools to the Aperio AI Store.

Oncology Researchers Gain AI Cancer Tools in One Platform