Changes in gene expression also hint at how the brains of people with ASD develop differently from those of other people.

Since their discovery in 2006, induced pluripotent stem cells have been poised to reprogram regenerative medicine. Twelve years on, here’s how far they’ve come.

This is the first time researchers have tested the use of the reprogrammed stem cells in the human brain.

Without knowing the cells’ mechanism of action, researchers question the best way to administer them to patients.

The $340 million, 30,000-square-foot center will produce cells for therapeutic applications.

Researchers use the technique to turn on Oct4 or Sox2 in mouse embryonic fibroblasts and convert them into pluripotent cells. 

The scientist was a member of a stem cell research team led by Nobel laureate Shinya Yamanaka. 

Michael Christman oversaw the organization’s well-known biobank and pioneered a personalized medicine initiative.

Combining gene editing and stem-cell induction improves efficiency of functional genetic analyses.