induced pluripotent stem cell
CRISPRi-Controlled Gene Expression
CRISPRi-Controlled Gene Expression
Jef Akst | Mar 10, 2016
A variation of the gene-editing technique can more precisely and efficiently downregulate the expression of target genes than traditional CRISPR/Cas9.
Mice Develop with Human Stem Cells
Mice Develop with Human Stem Cells
Karen Zusi | Dec 21, 2015
Human embryonic stem cells and induced pluripotent stem cells participated normally in early mouse embryo development in a recent study.
CIRM Ups Translational Velocity
CIRM Ups Translational Velocity
Bob Grant | Dec 21, 2015
California’s stem cell agency unveiled a 5-year plan that includes starting 50 new clinical trials.
Stem Cell Similarities
Stem Cell Similarities
Karen Zusi | Oct 28, 2015
Human induced pluripotent stem cells appear functionally equivalent to stem cells from embryos in a study.
Probing Down Syndrome with Mini Brains
Probing Down Syndrome with Mini Brains
Bob Grant | Oct 20, 2015
Researchers create cerebral organoids using induced pluripotent stem cells from patient skin cells and characterize protein-expression changes linked to cognitive impairment.
Mini-Kidneys from Stem Cells
Mini-Kidneys from Stem Cells
Jef Akst | Oct 7, 2015
Researchers grow kidney-like structures from human induced pluripotent stem cells.
Mitochondria Exchange
Mitochondria Exchange
Amanda B. Keener | Aug 26, 2015
A decade of research on intercellular mitochondrial transfer has answered some long-standing questions and raised new ones.
Chemical Cocktails Produce Neurons
Chemical Cocktails Produce Neurons
Kerry Grens | Aug 6, 2015
Two research groups have devised small-molecule recipes to directly transform fibroblasts into neurons.
Mitochondria Swap
Mitochondria Swap
Kate Yandell | Jul 15, 2015
Researchers generate patient-specific induced pluripotent stem cells corrected for mitochondrial defects.
Eye Stem Cell Therapy Moves Ahead
Eye Stem Cell Therapy Moves Ahead
Kate Yandell | Apr 30, 2015
Researchers inject retinal support cells derived from human embryonic stem cells into the eyes of four men with macular degeneration, bolstering evidence of the experimental treatment’s safety.