Salmonella (pink) invading a human epithelial cell (yellow)
Modified Salmonella Revs Immune Response, Combats Tumors in Mice
When coated with positively charged particles, the bacteria shuttled antigens out of tumors and activated the immune system, a study finds.
ABOVE: Flickr, NIAID
Modified Salmonella Revs Immune Response, Combats Tumors in Mice
Modified Salmonella Revs Immune Response, Combats Tumors in Mice

When coated with positively charged particles, the bacteria shuttled antigens out of tumors and activated the immune system, a study finds.

When coated with positively charged particles, the bacteria shuttled antigens out of tumors and activated the immune system, a study finds.

ABOVE: Flickr, NIAID

melanoma

A false-colored micrograph showing swirls of yellow, red, and magenta cells
Cross-Resistance: One Cancer Therapy Can Undermine the Next
Sophie Fessl | Jul 16, 2021
Targeted cancer therapy may jeopardize the effectiveness of subsequent immunotherapy by reducing dendritic cell numbers and activation, according to study of mice and patient samples.
An illustration of several DNA helices on a light red water color background
Human Blood Harbors Cell-Free Microbial DNA
Abby Olena | Jul 9, 2021
After controlling for high levels of bacterial contamination in their lab and reagents, researchers detect microbial genetic material in plasma samples from healthy people and cancer patients.
a leopard gecko with an unusually yellow body
“Lemon Frost” Leopard Geckos’ Cancers Similar to Human Melanomas
Christie Wilcox | Jun 24, 2021
The color morph’s bright yellow hue and its propensity for skin tumors both likely stem from a gene implicated in a dangerous form of human skin cancer, suggesting the animals could make an ideal model for studying the disease.
illustrations of cancer cells dividing in pink tones
Cancer Metastasizes Via Fusion of Tumor and Immune Cells: Study
Marcus A. Banks | Jun 17, 2021
Researchers say evidence of hybridization between leukocytes and cancer indicates that this is a primary means of metastasis. Others disagree.
Opinion: AI Could Aid Cancer Diagnosis, but Caution Is Needed
Adewole S. Adamson | Apr 1, 2021
While machine learning could improve detection of tumors at their earliest stages, it also risks identifying malignancies that would never cause the patient any harm.
George Preti, Organic Chemist Who Studied Human Body Odors, Dies
Amy Schleunes | Mar 20, 2020
Over nearly 50 years, the Monell Chemical Senses Center chemist investigated a range of topics, from the smell of cancer to body odor’s effects on human physiology and behavior.
Image of the Day: Melanoma Neural Network
Emily Makowski | Dec 9, 2019
A deep neural network can help determine how likely cancer cells are to metastasize.
custom targeted cancer vaccine
Personalized Cancer Vaccines in Clinical Trials
Jasreet Hundal, Elaine R. Mardis | Jul 15, 2019
The field is young, but predicting antigens produced by patients’ malignant cells could yield successful treatments for individuals with a range of cancer types.
Image of the Day: Bad Behavior
Kerry Grens | Dec 12, 2018
A deep learning program can identify cells with higher metastatic potential based on the way they look and move.
Immunotherapy Drug Shows Promise for Melanoma, Lung Cancer
Sukanya Charuchandra | Jun 4, 2018
Merck’s Keytruda extended the lives of lung cancer patients by several months and appeared to stop the progression of advanced melanoma.  
Caught on Camera
The Scientist Staff | Apr 1, 2018
Selected Images of the Day from the-scientist.com
Cancer-Fighting Chemical Found in Human Skin Bacteria
Diana Kwon | Mar 1, 2018
A molecule produced by a strain of Staphylococcus epidermis interferes with DNA synthesis.
Locally-Injected Immunotherapy Eradicates Tumors in Mice
Diana Kwon | Feb 1, 2018
The treatment also curbed the growth of nearby metastases that did not receive the drug.
Image of the Day: Sun Burn
The Scientist Staff, The Scientist Staff | Oct 20, 2017
When certain melanocyte stem cells are exposed to UV rays, a molecular cascade can trigger melanoma, scientists find in mice.
Cancers Relapse by Feeding Off Immune Signals
Shawna Williams | Oct 16, 2017
In mice, the tumor cells are able to thwart the immune response that would kill them—but immunotherapy prevented the return of melanoma.
Transgenic Mouse Illuminates Melanoma Metastasis
Abby Olena | Jun 28, 2017
Glowing cells mark the routes of tumor spread by way of newly formed lymph vessels. 
Rare T Cells Fight Cancer
Jef Akst | May 1, 2017
A new approach to immunotherapy finds that the immune-cell clonotypes that come to the rescue start out at very low frequencies.
Starvation Response Triggers Melanoma Invasion
Catherine Offord | Apr 1, 2017
Through similar mechanisms, amino acid depletion in culture and cytokine activity in the tumor microenvironment prompt cancer cells to metastasize.
Infographic: Inside Melanoma Invasion
Catherine Offord | Mar 31, 2017
See what cytokine activity and cellular starvation have to do with cancer metastasis.