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Explore How Stains and Probes Work to Label Cellular Morphology
Cellular Stains Under the Hood
Fluorescent probes are key tools for scientists looking at cellular properties or morphology. Use this guide to determine which probe is best for a given situation or experiment.
Cellular Stains Under the Hood
Cellular Stains Under the Hood

Fluorescent probes are key tools for scientists looking at cellular properties or morphology. Use this guide to determine which probe is best for a given situation or experiment.

Fluorescent probes are key tools for scientists looking at cellular properties or morphology. Use this guide to determine which probe is best for a given situation or experiment.

morphology

Image of a woolly mammoth skin from the Siberian permafrost.
Rebuilding the Genome of Woolly Mammoths
Laura Tran, PhD | Aug 19, 2024 | 4 min read
A well-preserved 52,000-year-old woolly mammoth skin sample with fossils of ancient chromosomes could offer a glimpse into the history of life.
An antenna-like cellular structure emerges from the surface of a human pancreatic islet cell. The surface of the cell is covered with small structures called microvilli.
The Shape of Cilia
Mariella Bodemeier Loayza Careaga, PhD | May 1, 2024 | 2 min read
Three dimensional images of human pancreatic islet cells provide an unprecedented view of the enigmatic primary cilia.
Defining the Triple Negative Breast Cancer Morpholome
Defining the Triple Negative Breast Cancer Morpholome
The Scientist Staff | 1 min read
Learn how researchers take a phenotype-first approach to uncover hidden metastatic drivers at tissue and cellular levels.
Infusion of Artificial Intelligence in Biology
Meenakshi Prabhune, PhD | Feb 23, 2024 | 10 min read
With deep learning methods revolutionizing life sciences, researchers bet on de novo proteins and cell mapping models to deliver customized precision medicines.
A Cape ground squirrel sits upright on its hind legs, holding its forelimbs up to its face.
Animals Are Shape-Shifting in Response to a Warming World
Andy Carstens | Jan 3, 2023 | 10 min read
Forced to respond to a climate that’s changing faster than it ever has, it remains unclear whether species’ adaptations can keep pace.
Beyond Skin Deep: Analyzing Melanoma Cells Through Morphology
Beyond Skin Deep: Analyzing Melanoma Cells Through Morphology
The Scientist | 1 min read
In this webinar, Evelyn Lattmann will discuss how she examined melanoma cell morphology without labels using an AI-based microscope system.  
Panels showing different kinds of microglia
Mapping Tool Reveals Microglia’s Shape-Shifting Secrets
Angie Voyles Askham, Spectrum | Dec 14, 2022 | 4 min read
The approach could help test hypotheses about how atypical function of the brain’s immune cells contributes to autism.
Artist’s rendering of an early mammal called a mammaliamorph
Warm-Bloodedness in Mammals May Have Arisen in Late Triassic
Andy Carstens | Jul 21, 2022 | 2 min read
Researchers mapped ear canal shape to body temperature to predict when ancestors of mammals first became endothermic.
A multicolored illustration of a cell undergoing division.
See Beyond the Scatter Plot with Imaging, Spectral Flow Cytometry
The Scientist and BD Biosciences | 3 min read
A novel instrument combines fluorescence-activated cell sorting, imaging flow cytometry, and spectral flow cytometry to advance cell population examination.
The fossil tooth found in the Annamite Mountains in Laos
Ancient Tooth Could Be Clue in Denisovan Migration Mystery
Andy Carstens | May 18, 2022 | 2 min read
The new fossil from Laos helps answer the question of how some people from Oceania carry DNA from the ancient hominin.
Image of not-to-scale renderings of the skulls of various primate species
Surface Area of Tooth Roots Predicts Primate Body Size
Maddie Bender | May 2, 2022 | 2 min read
Researchers determine that a primate’s tooth root, and not just its crown, can yield reliable information about body size, but the relationship between root surface area and diet isn’t as clear.
Technique Talk: Developing and Optimizing Immunohistochemistry Protocols
Technique Talk: Developing and Optimizing Immunohistochemistry Protocols
The Scientist | 1 min read
Learn about the fundamentals of immunohistochemistry in this workshop for better protocol development and troubleshooting.
shrew
Researchers Identify 14 New Shrew Species 
Chloe Tenn | Jan 5, 2022 | 2 min read
The discovery, made on the island of Sulawesi in Indonesia, constitutes an exceptionally high number of new mammals to be described in a single paper.
two quails
Chromosomal Rearrangement Linked to Less Mobile Quail
Chloe Tenn | Dec 7, 2021 | 5 min read
The Scientist interviews evolutionary biologist Carles Vilà about how a large genomic inversion detected in common quail affects the birds’ physical characteristics and migratory behaviors.
Visualizing apoptosis in a DU-145 cancer cell
Observing Cells in Their Natural State with Digital Holographic Cytometry
The Scientist and Phase Holographic Imaging | 3 min read
Technological and engineering advances let researchers delve deeper into cell function and behavior in physiological and pathological settings.
The man-of-war fish (Nomeus gronovii), a species of medusafish, near the tentacles of a siphonophore.
Medusafishes Are Grouped by Shared, Odd Traits: Study
Devin A. Reese, PhD | Dec 1, 2021 | 2 min read
Shared features, such as thick, slimy skin and a throat filled with teeth, suggest that medusafishes are all related.
Infographic: Anatomical Construction by Cell Collectives
Michael Levin | Sep 1, 2020 | 3 min read
Understanding this complex and still largely enigmatic process will pave the way for researchers to control the development of new morphologies.
Technique Talk: The Basics of Immunohistochemistry
The Scientist | 1 min read
Learn about the fundamentals of immunohistochemistry in this workshop for better protocol development and troubleshooting.
How Groups of Cells Cooperate to Build Organs and Organisms
Michael Levin | Sep 1, 2020 | 10+ min read
Understanding biology’s software—the rules that enable great plasticity in how cell collectives generate reliable anatomies—is key to advancing tissue engineering and regenerative medicine.
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