What we can know about biology before the last universal common ancestor is limited—and we should be circumspect in filling in the gaps.

In audio files from 2005, the future Administrator of the EPA said there’s a lack of “sufficient scientific facts” to back the theory.

Reactions that generate fundamental components of the cell run smoothly in microdroplets, study shows.

Embedded within 3.95-billion-year-old rock, scientists have found graphite with a carbon signature that indicates biological activity.

A newly discovered superphylum of archaea may be related to a microbe that engulfed a bacterium to give rise to complex eukaryotic life.

Researchers show how RNA bases could self-assemble in conditions that might resemble Earth’s primordial soup.

Harold Morowitz, who dedicated his career to investigating the origins of life, has passed away at age 88.

A new estimate of the origin of life on Earth pushes back the date by 300 million years.

New research points to key properties of transfer RNA molecules and amino acids that may have supported the origin of life on Earth.

Mathematical and computational approaches are making strides in understanding how life might have emerged and organized itself from the basic chemistry of early Earth.