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a white mouse sits on a blue exercise wheel, looking out onto the shavings below
Mice With a Healthy Gut Microbiome Are More Motivated to Exercise
A neural pathway between the gut and the brain led to the release of dopamine when the mice ran on a wheel or treadmill, but only in the presence of a robust microbiome. 
Mice With a Healthy Gut Microbiome Are More Motivated to Exercise
Mice With a Healthy Gut Microbiome Are More Motivated to Exercise

A neural pathway between the gut and the brain led to the release of dopamine when the mice ran on a wheel or treadmill, but only in the presence of a robust microbiome. 

A neural pathway between the gut and the brain led to the release of dopamine when the mice ran on a wheel or treadmill, but only in the presence of a robust microbiome. 

pathway
Human hand with white glove holding a white mouse in a green background.
Study Traces a Neural Circuit Behind Green Light–Mediated Pain Relief
Alejandra Manjarrez, PhD | Dec 9, 2022 | 4 min read
A mouse study concludes color-detecting cones in the eye and a subset of neurons in the brain’s thalamus are why green light exposure has an analgesic effect.
Circular clusters of <em>Staphylococcus aureus</em> drift on a blue background.
Retching Mice Reveal the Brain Circuit Behind Vomiting
Katherine Irving | Nov 2, 2022 | 2 min read
The discovery could one day lead to the development of better antinausea medications.
a false color transmission electron microscope image of a neuronal cell body, with lysosomes colored dark green
Scientists Uncover Major Pathway Cells Use to Mend Leaky Lysosomes
Holly Barker | Oct 6, 2022 | 3 min read
Damaged lysosomes are repaired by a lipid-based signaling pathway dubbed PITT that could be targeted to treat neurodegenerative disease, its discoverers say.
mice on wheel and ground
Exercise-Associated Protein Boosts Brain Function in Mice
Chloe Tenn | Dec 9, 2021 | 5 min read
A study that transfused plasma from active to inactive mice suggests the protein clusterin enhances cognition.
group of people
HHMI Kickstarts $2 Billion Initiative to Boost Diversity in STEM
Chloe Tenn | Nov 23, 2021 | 7 min read
The Howard Hughes Medical Institute will invest the funds over 10 years across all stages of the STEM pipeline.
Photograph of a mouse covering his face with his paw.
Bless You: Mouse Model Reveals Molecular Pathway Behind Sneezing
Amanda Heidt | Oct 1, 2021 | 3 min read
Researchers have identified specific cells and neuropeptides involved in mediating the sneeze response in mice exposed to allergens or chemical irritants such as capsaicin.
Illustration showing how a mouse study identifies the brain regions and specific signaling factors that regulate the sneeze response.
Infographic: The Neural Pathway of Sneezing
Amanda Heidt | Oct 1, 2021 | 1 min read
A mouse study identifies the brain regions and specific signaling factors that regulate the sneeze response.
traced mouse neurons
Image of the Day: Brain Map
Nicoletta Lanese | Sep 6, 2019 | 1 min read
Scientists traced 1,000 neurons through the mouse brain, uncovering new details about how the organ is wired.
RNA World 2.0
Jef Akst | Mar 1, 2014 | 10+ min read
Most scientists believe that ribonucleic acid played a key role in the origin of life on Earth, but the versatile molecule isn’t the whole story.
 
Cartographer of Metabolic Pathways Dies
Edyta Zielinska | Jun 4, 2012 | 1 min read
A biochemist who mapped the ways in which molecular pathways interact passed away at age 96.
New Kind of Cellular Suicide
Jef Akst | Feb 23, 2012 | 1 min read
Researchers identify a gene that drives a type of cellular suicide that differs from the more commonly observed apoptosis phenomenon.
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