Prime Editing News, Articles | The Scientist Magazine®

Can “Gene Writing” Deliver What Gene Editing Can’t?

A biotech startup called Tessera Therapeutics has made a splash with its claims about the trademarked technology. Is the excitement justified?

Can “Gene Writing” Deliver What Gene Editing Can’t?

A biotech startup called Tessera Therapeutics has made a splash with its claims about the trademarked technology. Is the excitement justified?

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Infographic: Two Guide RNAs Make for Large, Stable Insertions

Dan Robitzski | Jun 13, 2022 | 1 min read

A new technique goes beyond CRISPR and writes two complementary strands of DNA directly into the genome.

Genetic Syndrome and Genetic Disorder, 3D illustration of science concept.

With Two RNA Guides, Editing Technique Writes Long DNA Insertions

Dan Robitzski | Jun 13, 2022 | 3 min read

The approach, called GRAND, uses a second guide RNA to write complementary strands of DNA in targeted genomic locations, resulting in efficient insertions that can be hundreds of base pairs long.

prime editing crispr cas9 genome editing techniques

New “Prime Editing” Method Makes Only Single-Stranded DNA Cuts

Emma Yasinski | Oct 21, 2019 | 4 min read

In demonstrations in cell lines, the technique has a similar efficacy to CRISPR-Cas9, but fewer off-target effects.