promoters

The FDA pauses the research program on a lentivirus-based treatment for a rare neurological condition after a patient developed a bone marrow disorder that could presage leukemia.

New analyses find that divergent transcription, in which one promoter directs the expression of two adjacent genes oriented in opposite directions, is conserved across all domains of life.

Two research teams develop tools for tinkering with a bacterial genus prominent in human guts.

Two new techniques allow researchers to manipulate the activity of gut bacteria. 

A chromatin remodeler in embryonic stem cells clears the DNA for mRNA transcription while stifling the expression of noncoding transcripts.

A new full-genome map indicates how DNA is folded within the nuclei of human cells.

Tweaking the expression of guide RNAs used in CRISPR genome editing broadens the repertoire of target sites.

Scientists have recently discovered that enhancers are often transcribed into RNAs. But they’re still not sure what, if anything, these eRNAs do.

Consortium annotates the human genome with cell type-specific information about transcription start sites, active enhancers, and their expression throughout the body.

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