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How Immature Egg Cells in Ovaries Resist Aging
The cells’ mitochondria skip a key metabolic reaction that takes place in other cells in the body, a study finds.
How Immature Egg Cells in Ovaries Resist Aging
How Immature Egg Cells in Ovaries Resist Aging

The cells’ mitochondria skip a key metabolic reaction that takes place in other cells in the body, a study finds.

The cells’ mitochondria skip a key metabolic reaction that takes place in other cells in the body, a study finds.

reactive oxygen species
Mouse heart cells that have taken up adipocyte-derived extracellular vesicles (stained red)
Fat Cells Send Mitochondrial Distress Signals to the Heart
Ruth Williams | Aug 20, 2021 | 3 min read
Vesicles containing fragments of the organelles released from stressed adipocytes protect the heart against oxygen deprivation, a study in mice shows.
amphibian hindlimb chicken animal feet hand development reactive oxygen species fingers digits webbing webbed
Image of the Day: Phantom Limbs
Chia-Yi Hou | Jun 17, 2019 | 1 min read
Researchers study how oxygen around an embryo helps shape the way feet and digits form in amphibians and chickens.
 Learn how excessive oxygen availability during cell culture causes abnormal cell behavior 
What Oxygen Level Is Biologically Relevant For Cell Culture?
Thermo Fisher Scientific | 1 min read
Normoxic atmospheric conditions provide excessive oxygen availability, leading to abnormal cell behavior.
Weak Magnetic Fields Manipulate Regeneration in Worms
Ruth Williams | Jan 30, 2019 | 3 min read
At magnetic field intensities somewhat above that of Earth, stem cell proliferation shifts gears.
Mitochondria Play an Unexpected Role in Killing Bacteria
Katarina Zimmer | Jan 1, 2019 | 3 min read
The energy-producing organelles also send out parcels with antimicrobial compounds to help destroy pathogen invaders in macrophages.
Muscle immobilization leads to atrophy
Antioxidants Put the Pep Back in One’s Step
Niki Spahich, PhD | 3 min read
Delivering antioxidants via extracellular vesicles to atrophied muscles restores them during rehabilitation.
Old Age Has Links to Redox Stress in Muscles
Sukanya Charuchandra | Sep 1, 2018 | 2 min read
Even if people exercise, hydrogen peroxide and other reactive molecules continue to accumulate in the tissues.
Image of the Day: Not All Bad
Sukanya Charuchandra | Jul 16, 2018 | 1 min read
In zebrafish, some amount of reactive oxygen species is required for normal development.
Discover how to scale up cellular assays during drug discovery
High-Throughput Solutions for Lead Candidate Discovery
The Scientist Creative Services Team and Thermo Fisher Scientific | 1 min read
New technologies allow researchers to scale up assays for cellular functions.
Elena Rybak-Akimova, Chemical Kinetics Expert, Dies
Jim Daley | Mar 16, 2018 | 2 min read
The chemist examined the role of activated oxygen molecules in biological processes.
Caught in the Act
Devika G. Bansal | Nov 1, 2017 | 6 min read
Molecular probes for imaging in live animals
Study Bucks Belief that Oxidative Stress Is Bad for Pregnancy
Jef Akst | May 16, 2017 | 2 min read
Mouse experiments indicate that, contrary to observations in pregnant women, reactive oxygen species contribute to normal placental development.
Antioxidants Again Linked to Cancer’s Spread
Anna Azvolinsky | Apr 13, 2016 | 3 min read
Certain diabetes drugs with antioxidant properties promote metastasis in mice with existing tumors, researchers report.
New Route to Hearing Loss Mapped
Kerry Grens | Nov 5, 2015 | 3 min read
Deficiency in a protein called pejvakin makes inner ear cells more vulnerable to sound, unable to brace themselves against oxidative stress stimulated by noise. 
Antioxidants Facilitate Melanoma Metastasis
Anna Azvolinsky | Oct 7, 2015 | 3 min read
Two compounds boost the ability of melanoma cells to invade other tissues in mice, providing additional evidence that antioxidants can be beneficial to malignant cells as well as healthy ones.
ROS Can Shorten or Lengthen Life
Kerry Grens | Feb 13, 2015 | 1 min read
Reactive oxygen species have opposing effects on roundworm longevity depending on whether these molecules are in the mitochondria or the cytoplasm.
The Energizer
Megan Scudellari | May 1, 2014 | 8 min read
György Hajnóczky uncovers the chemical and physical strategies by which mitochondria communicate and function within a cell.
The Downside of Antibiotics?
Ruth Williams | Jul 3, 2013 | 3 min read
Bacteria-killing antibiotics might also damage a person’s tissues.
Shielding Cancer Cells from Damage
Tia Ghose | Nov 3, 2011 | 2 min read
An alternative form of an enzyme involved in the glucose metabolism pathway protects cancer cells from oxidative stress.
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