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Human Pancreas Cells Can Be Made to Produce Insulin
Jef Akst | Feb 14, 2019
When implanted into mice, the “pseudo-islets” helped treat the animals’ diabetes symptoms.
Chinese Scientist Sentenced to 10 Years in Prison for Rice-Smuggling Plot
Ashley Yeager | Apr 5, 2018
The researcher stole genetically modified seeds and planned to give them to a crop research institute in China, the US Justice Department says.
Partial Reprogramming Offers a Way to Generate High Volumes of Progenitor-Like Cells
Abby Olena | Nov 30, 2017
Activating genes for reprogramming factors for a short time transforms large numbers of differentiated cells into multipotent forms that could be useful for cell-based therapies.
Reprogrammed Glia Improve Symptoms in a Mouse Model of Parkinson’s
Diana Kwon | Apr 10, 2017
By converting glial cells into dopaminergic neurons, scientists were able to partially rescue motor behavior in mice.
Stem Cells Made Waves in Biology and Medicine
Karen Zusi | Oct 1, 2016
Since their introduction to the lab, pluripotent stem cells have gone from research tool to therapeutic, but the journey has been rocky.
Study: Mitotic Cells Can Reprogram Mouse Sperm
Ashley P. Taylor | Sep 13, 2016
Murine embryos undergoing first cell division can reprogram injected sperm and develop normally.
With CRISPR, Scientists Make Neurons From Fibroblasts
Kerry Grens | Aug 15, 2016
Researchers use the CRISPR/Cas system to express three transcription-factor genes, changing the identities of mouse cells.
Programming Pancreatic Cells
Catherine Offord | Jan 6, 2016
Researchers reprogram human skin cells to make insulin-producing pancreatic cells that can prevent diabetes in mice.
Kate Yandell | Jan 1, 2016
A tour of efforts to automate the production and differentiation of induced pluripotent stem cells
Stem Cell Similarities
Karen Zusi | Oct 28, 2015
Human induced pluripotent stem cells appear functionally equivalent to stem cells from embryos in a study.
Neurons from Glia In Vivo
Kerry Grens | Oct 19, 2015
Scientists present new recipes for directly converting glial cells to neurons in mouse brains.
Chemical Cocktails Produce Neurons
Kerry Grens | Aug 6, 2015
Two research groups have devised small-molecule recipes to directly transform fibroblasts into neurons.
Mary Beth Aberlin | Aug 1, 2015
The animal world is full of clever solutions to bioengineering challenges.
Leaving an Imprint
Anna Azvolinsky | Aug 1, 2015
Among the first to discover epigenetic reprogramming during mammalian development, Wolf Reik has been studying the dynamics of the epigenome for 30 years.
2014’s Big Advances in Science
Kerry Grens | Dec 24, 2014
From artificial chromosomes to mind-controlled gene expression, scientists pushed the boundaries of manipulating biology this year.
STAP Author Can’t Replicate Results
Kerry Grens | Dec 22, 2014
RIKEN’s Haruko Obokata fails to replicate stimulus-triggered acquisition of pluripotency.
Anna Azvolinsky | Dec 18, 2014
Can mechanical forces alone be manipulated to create stem-like cells?
New Stem Cell State
Anna Azvolinsky | Dec 10, 2014
Through cellular reprogramming, researchers have produced a novel pluripotent mouse stem cell in vitro.
Next Generation: Biological Pacemakers
Ruth Williams | Jul 16, 2014
Direct reprogramming of cardiac muscle cells into pacemaker cells gives pig hearts back their rhythm.
Not All Stem Cells Created Equal
Anna Azvolinsky | Jul 2, 2014
Compared to induced pluripotent stem cells generated from somatic cells, stem cells created by nuclear transfer appear to be closer to the genetic state of embryonic cells.