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Cross section of an organic cell with intracellular organelles
How Intracellular Bacteria Hijack Your Cells
Scientists studying pathogens such as Chlamydia, Legionella, and Listeria get a master class in how to control the internal workings of mammalian cells.
How Intracellular Bacteria Hijack Your Cells
How Intracellular Bacteria Hijack Your Cells

Scientists studying pathogens such as Chlamydia, Legionella, and Listeria get a master class in how to control the internal workings of mammalian cells.

Scientists studying pathogens such as Chlamydia, Legionella, and Listeria get a master class in how to control the internal workings of mammalian cells.

reprogramming
Illustration showing how some intracellular bacteria, such as <em >Legionella pneumophila</em>, manipulate the cell&#39;s membranes for their own good
Infographic: Intracellular Bacteria’s Tricks for Host Manipulation 
Catherine Offord | Dec 1, 2022 | 2 min read
Various microbes, including several human pathogens, hijack the cell’s skeleton, membranes, and protein-making machinery to make themselves at home.
Human Pancreas Cells Can Be Made to Produce Insulin
Jef Akst | Feb 14, 2019 | 2 min read
When implanted into mice, the “pseudo-islets” helped treat the animals’ diabetes symptoms.
A reprogrammed astrocyte that can regenerate functional neurons.
Reprogramming Astrocytes: Unlocking DLX2’s Potential to Mend the Brain
Nele Haelterman, PhD | 3 min read
Scientists discover how to convert the brain’s glial cells into multipotent neural stem cells.
Chinese Scientist Sentenced to 10 Years in Prison for Rice-Smuggling Plot
Ashley Yeager | Apr 5, 2018 | 2 min read
The researcher stole genetically modified seeds and planned to give them to a crop research institute in China, the US Justice Department says.
Partial Reprogramming Offers a Way to Generate High Volumes of Progenitor-Like Cells
Abby Olena, PhD | Nov 30, 2017 | 3 min read
Activating genes for reprogramming factors for a short time transforms large numbers of differentiated cells into multipotent forms that could be useful for cell-based therapies.
Reprogrammed Glia Improve Symptoms in a Mouse Model of Parkinson’s
Diana Kwon | Apr 10, 2017 | 3 min read
By converting glial cells into dopaminergic neurons, scientists were able to partially rescue motor behavior in mice.
Stem Cells Made Waves in Biology and Medicine
Karen Zusi | Oct 1, 2016 | 6 min read
Since their introduction to the lab, pluripotent stem cells have gone from research tool to therapeutic, but the journey has been rocky.
Study: Mitotic Cells Can Reprogram Mouse Sperm
Ashley P. Taylor | Sep 13, 2016 | 4 min read
Murine embryos undergoing first cell division can reprogram injected sperm and develop normally. 
With CRISPR, Scientists Make Neurons From Fibroblasts
Kerry Grens | Aug 15, 2016 | 1 min read
Researchers use the CRISPR/Cas system to express three transcription-factor genes, changing the identities of mouse cells.
Programming Pancreatic Cells
Catherine Offord | Jan 6, 2016 | 2 min read
Researchers reprogram human skin cells to make insulin-producing pancreatic cells that can prevent diabetes in mice.
Pluripotency Bots
Kate Yandell | Jan 1, 2016 | 8 min read
A tour of efforts to automate the production and differentiation of induced pluripotent stem cells
Stem Cell Similarities
Karen Zusi | Oct 28, 2015 | 2 min read
Human induced pluripotent stem cells appear functionally equivalent to stem cells from embryos in a study.
Neurons from Glia In Vivo
Kerry Grens | Oct 19, 2015 | 2 min read
Scientists present new recipes for directly converting glial cells to neurons in mouse brains.
Chemical Cocktails Produce Neurons
Kerry Grens | Aug 6, 2015 | 3 min read
Two research groups have devised small-molecule recipes to directly transform fibroblasts into neurons.
Mimicry Muses
Mary Beth Aberlin | Aug 1, 2015 | 2 min read
The animal world is full of clever solutions to bioengineering challenges.
Leaving an Imprint
Anna Azvolinsky | Aug 1, 2015 | 8 min read
Among the first to discover epigenetic reprogramming during mammalian development, Wolf Reik has been studying the dynamics of the epigenome for 30 years.
2014’s Big Advances in Science
Kerry Grens | Dec 24, 2014 | 4 min read
From artificial chromosomes to mind-controlled gene expression, scientists pushed the boundaries of manipulating biology this year.
STAP Author Can’t Replicate Results
Kerry Grens | Dec 22, 2014 | 1 min read
RIKEN’s Haruko Obokata fails to replicate stimulus-triggered acquisition of pluripotency.
Reprogramming Redux
Anna Azvolinsky | Dec 18, 2014 | 3 min read
Can mechanical forces alone be manipulated to create stem-like cells?
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