Single-cell genome analyses reveal the amount of mutations a human brain cell will collect from its fetal beginnings until death.

Advances in single-cell technologies have revealed vast differences between cells once thought to be in the same category, calling into question how we define cell type in the first place.

Genomic analysis of an oak tree that lived during Napoleon’s time supports the idea that plants somehow avoid the accumulation of mutations in their stem cells.

A follow-up study confirms that random mutations acquired during normal stem cell division likely play a major role in cancer incidence.

A new algorithm reveals hoards of preparation-induced DNA mutations in publicly available human sequences.

Scientists produce a detailed genomic map of mutations and epigenetic changes associated with smoking tobacco across 17 tumor types. 

Researchers examine the role of long interspersed element-1 retrotransposition in neuronal mosaicism.

Induced pluripotent stem cells—particularly those generated from older patients—should be screened for defects in mitochondrial DNA, a study shows.

The mutation rate in induced pluripotent stem cells is 10 times lower than in somatic cells, scientists show.

Somatic mosaicism may be responsible for a larger proportion of genomic variability within humans than previously thought.