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Prolonged GLP-1 Exposure Remodels Gene Expression in the Pancreas by Flipping a Molecular Switch
Long-term GLP-1 exposure drives phosphorylation of a key protein, resulting in massive changes in gene expression and partial reprogramming of pancreatic beta cells.
Lawnmower-like Enzyme Rewinds Decades of Molecular Aging in Human Tissue
An engineered enzyme cleaved and repaired age-related protein damage in human tissue, which was long thought to be irreversible in a proof-of-concept study.
How the Gut Differentiates Artificial Sweeteners from Sugars
Signals from sweeteners and sugars are relayed from the gut to the brain by different neural pathways, a new study concludes.
Female Brains Wake Up from Anesthesia Differently Than Male Brains
Ketamine anesthesia drives female-specific microglial activity in mice, offering insight about the anesthetic and highlighting the need to study sex as a biological variable.
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Improving rAAV Production for Viral Vector Manufacturing
Explore strategies for improving recombinant adeno-associated virus production in transient HEK293 suspension cultures while maintaining vector quality and supporting scalable viral vector manufacturing.
Managing Complexity in NGS Library Preparation
Explore how automation can simplify demanding steps and support consistent processing across normalization, cleanup, and size selection.
